ReviewFrontiers in psychiatry2020
Cannabis Legalization and Acute Harm From High Potency Cannabis Products: A Narrative Review and Recommendations for Public Health.
Review in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.
- Pharmacotherapies for cannabis use disorder.The Cochrane database of systematic reviews · 2025Pooled it
- A social media intervention for cannabis use among emerging adults: Randomized controlled trial.Drug and alcohol dependence · 2022Trial
- Surveillance of Cannabis Strains Using Online Data: Observational Study.JMIR formative research · 2026Observational
- Cognitive performance and subjective effects the morning after last use of smoked cannabis by adults who use cannabis frequently: An observational study.Drug and alcohol dependence reports · 2026Article
- An update on cannabis products, cannabinoid content, plant type, and prices five years after legalization in Ontario, Canada.Journal of cannabis research · 2026Article
- Narrowing and Reversing Sex Gaps in Cannabis Use and Cannabis Use Disorder Among Adolescents and Young Adults.Journal of studies on alcohol and drugs · 2026Article
- Lessons learned: challenges in recruiting and engaging people with heavy cannabis use for online interventions in Canada.Journal of cannabis research · 2026Article
- Adult-use cannabis legalization in the united states: a scoping review of outcome monitoring recommendations.BMC public health · 2025Article
- Association of Preconception and Prenatal Cannabis Use With Breastfeeding.American journal of preventive medicine · 2025Article
- Cannabinoid Hyperemesis Syndrome, 2016 to 2022.JAMA network open · 2025Article
- Perceptions of cannabis among adults aged 60 years and older in Canada: a qualitative study.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2025Article
- A content analysis of cannabis edible product characteristics, packaging features, and online promotions.Preventive medicine · 2025Article
- Cannabis use is associated with changes in psychological and functional well-being during young adulthood: evidence from self-reports and hair analyses.Psychological medicine · 2025Article
- Trends in cannabis-attributable hospitalizations and emergency department visits: data from the Canadian Substance Use Costs and Harms Study (2007-2020).Health promotion and chronic disease prevention in Canada : research, policy and practice · 2025Article
- Multilevel determinants of cannabis prices in legal markets: Evidence from products sold in nearly 4000 cannabis dispensaries in the United States.The International journal on drug policy · 2025Article
- Impact of Early-Life Adversity on Cannabis Use: Exploring the Mediating and Moderating Effects of Chronic Pain.Cannabis and cannabinoid research · 2025Article
- Editorial: Cannabis and cannabinoids in psychiatry.Frontiers in public health · 2025Article
- Cannabis Use Characteristics and Reasons for Product Choices Among Patients Accessing Treatment for Substance Use Disorders: A Mixed-Methods Study.Cannabis (Albuquerque, N.M.) · 2025Article
- Cannabis use disorder: from neurobiology to treatment.The Journal of clinical investigation · 2024Review
- Examining the Popularity, Content, and Intersections With the Substance Abuse and Mental Health Services Administration's Definition of Recovery in a Nonclinical Online Cannabis Cessation Community: Infodemiology Study of Reddit Posts.Journal of medical Internet research · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Legalization and commercial sale of non-medical cannabis has led to increasing diversity and potency of cannabis products. Some of the American states that were the first to legalize have seen rises in acute harms associated with cannabis use, e.g. Colorado has seen increases in emergency department visits for cannabis-related acute psychological distress and severe vomiting (hyperemesis), as well as a number of high-profile deaths related to ingestion of high doses of cannabis edibles. Over-ingestion of cannabis is related to multiple factors, including the sale of cannabis products with high levels of THC and consumers' confusion regarding labelling of cannabis products, which disproportionately impact new or inexperienced users. Based on our review of the literature, we propose three approaches to minimizing acute harms: early restriction of cannabis edibles and high-potency products; clear and consistent labelling that communicates dose/serving size and health risks; and implementation of robust data collection frameworks to monitor harms, broken down by cannabis product type (e.g. dose, potency, route of administration) and consumer characteristics (e.g. age, sex, gender, ethnicity). Ongoing data collection and monitoring of harms in jurisdictions that have existing legal cannabis laws will be vital to understanding the impact of cannabis legalization and maximizing public health benefits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.