ArticleCase reports in oncology
Metastases from Occult Breast Cancer: A Case Report of Carcinoma of Unknown Primary Syndrome.
Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Deep Learning for Early Breast Cancer Detection on Contrast-Enhanced Breast MRI: A Multicenter Study.Cancers · 2026Article
- Occult Breast Cancer Initially Presenting with Axillary Lymph Node Metastasis: A Case Report.Journal of the Korean Society of Radiology · 2025Article
- AI in 2D Mammography: Improving Breast Cancer Screening Accuracy.Medicina (Kaunas, Lithuania) · 2025Article
- Occult breast cancer in an older woman: A case report.Experimental and therapeutic medicine · 2025Article
- Occult Breast Cancer Diagnosed from a Solitary Scalp Metastasis without Axillary Lymph Node Involvement: A Case Report.Surgical case reports · 2025Article
- Article
- Breast Cancer Detection and Analytics Using Hybrid CNN and Extreme Learning Machine.Journal of personalized medicine · 2024Article
- Current Trends and Beyond Conventional Approaches: Advancements in Breast Cancer Surgery through Three-Dimensional Imaging, Virtual Reality, Augmented Reality, and the Emerging Metaverse.Journal of clinical medicine · 2024Review
- Obesity-Associated Breast Cancer: Analysis of Risk Factors and Current Clinical Evaluation.Advances in experimental medicine and biology · 2024Review
- Occult primary breast cancer: Two cases report and literature review.International journal of surgery case reports · 2023Article
- Occult breast cancer with pleural metastasis.Radiology case reports · 2023Article
- The Elusive Primary: Metastatic Adenocarcinoma of the Breast Presenting Solely as a Hard Sternal Mass.The American journal of case reports · 2023Article
- Regional Lymph Node Metastasis and Axillary Surgery of Microinvasive Breast Cancer: A Population-Based Study.Diagnostics (Basel, Switzerland) · 2022Article
- Lymphatic Endothelial Markers and Tumor Lymphangiogenesis Assessment in Human Breast Cancer.Diagnostics (Basel, Switzerland) · 2021Review
- Invasive Cystic Hypersecretory Ductal Carcinoma of Breast: Challenges in Diagnosis and Management.Case reports in oncologyArticle
- Unusual Metastatic Lymph Node to Retro-Scapular Area in Occult Breast Cancer: A Case Report.Case reports in oncologyArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carcinoma of unknown primary (CUP) syndrome occurs when metastases from an unknown primary site spread to multiple organs. Occult breast cancer (OBC) is defined as a clinically recognizable metastatic carcinoma from an undetectable primary breast tumor. It accounts for 0.3-1% of all breast cancers, often presenting with lymph node, bone, and skin metastases. Clinical and radiological examinations represent the first steps in the diagnostic algorithm for CUP syndrome from OBC. However, histological and immunohistochemical analyses, multidisciplinary team evaluation, and a multidisciplinary therapy are essential in the diagnosis and treatment of CUP syndrome from OBC. We report the case of a 52-year-old woman who underwent the removal of a parietal skin lesion. The histological and immunohistochemical analyses suggested a breast cancer origin. Clinical assessment and laboratory and radiological examinations did not locate the primary tumor. Hormone therapy was offered to the patient; however, she refused it. After 28 months, the patient reported a right cervical lump, and a total-body positron emission tomography showed dissemination of the disease to the lymph nodes and bone. A CUP syndrome from OBC was diagnosed. A multimodality approach with radiotherapy and hormone and biological therapy was started. At present, 5 years from the first presentation, the patient is asymptomatic despite the disseminated disease.
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