ReviewClinical interventions in aging2020
Cardiac Cachexia: A Well-Known but Challenging Complication of Heart Failure.
Review in Clinical interventions in aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Differences in peak oxygen uptake in heart failure patients with and without cachexia: A systematic review and meta-analysis.Physiological reports · 2025Pooled it
- Multimodal interventions for cachexia management.The Cochrane database of systematic reviews · 2025Pooled it
- Post-prandial acyl ghrelin infusion in heart failure patients increases gastric emptying rate.Naunyn-Schmiedeberg's archives of pharmacology · 2026Trial
- Association Between Cachexia Defined by the Asian Working Group for Cachexia Criteria and One-Year Post-Discharge Mortality in Older Adults with Acute Decompensated Heart Failure.Geriatrics (Basel, Switzerland) · 2026Article
- The impact of preoperative weight loss on recovery after cardiac surgery.Heart and vessels · 2026Article
- Cardiovascular remodeling: key mechanisms and clinical implications linking sarcopenia and heart failure.Frontiers in medicine · 2026Review
- Modified body mass index as a novel prognostic indicator of in-hospital mortality after off-pump coronary artery bypass grafting: A nationwide multicenter cohort study.International journal of cardiology. Heart & vasculature · 2025Article
- When the Heart, Kidneys, and Body Waste Away: A Review of Cachexia in Cardiorenal Syndrome.Current heart failure reports · 2025Review
- Beyond the Scale: The Hidden Burden of Underweight and Cachexia in Adults with Congenital Heart Defects and Heart Failure-Results from the Pathfinder CHD-Registry.Journal of clinical medicine · 2025Article
- One Size Does Not Fit All: Reassessment of The Prognostic Nutritional Index Among Geriatric Distal Femur Fracture Patients.Archives of orthopaedic and trauma surgery · 2025Article
- Navigating Sarcopenia Risks in GLP-1RA Therapy for Advanced Heart Failure.Biomedicines · 2025Review
- Recovery of Physical Function during Hospitalization among Heart Failure Patients with and without Cachexia.Physical therapy research · 2025Article
- The lived experience of renal cachexia: An interpretive phenomenological analysis.International journal of nursing studies advances · 2024Article
- Targeting MuRF1 to Combat Skeletal Muscle Wasting in Cardiac Cachexia: Mechanisms and Therapeutic Prospects.Medical science monitor : international medical journal of experimental and clinical research · 2024Review
- Review
- Nutritional Assessment in Outpatients with Heart Failure.Nutrients · 2024Observational
- Nutritional Status and Post-Cardiac Surgery Outcomes: An Updated Review with Emphasis on Cognitive Function.Journal of clinical medicine · 2024Review
- Metabolomic insights in advanced cardiomyopathy of chronic chagasic and idiopathic patients that underwent heart transplant.Scientific reports · 2024Article
- Excessive fat expenditure in MCT-induced heart failure rats is associated with BMAL1/REV-ERBα circadian rhythmic loop disruption.Scientific reports · 2024Article
- Differences in Health-Related Quality of Life among Patients with Heart Failure.Medicina (Kaunas, Lithuania) · 2024Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heart failure (HF) is a common complication of various cardiac diseases, and its incidence constantly increases. This is caused mainly by aging of populations and improvement in the treatment of coronary artery disease. As HF patients age, they tend to develop comorbidities, creating new problems for health-care professionals. Sarcopenia, defined as the loss of muscle mass and function, and cachexia, defined as weight loss due to an underlying illness, are muscle wasting disorders of particular relevance in the heart failure population, but they go mostly unrecognized. The coexistence of chronic HF and metabolic disorders facilitates the development of cachexia. Cachexia, in turn, significantly worsens a patient's prognosis and quality of life. The mechanisms underlying cachexia have not been explained yet and require further research. Understanding its background is crucial in the development of treatment strategies to prevent and treat tissue wasting. There are currently no specific European guidelines or recommended therapy for cachexia treatment in HF ("cardiac cachexia").
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.