Evidence map›Paper›PMID 33173238›Full record

ArticleGeburtshilfe und Frauenheilkunde2020

Update Breast Cancer 2020 Part 3 - Early Breast Cancer.

Jens Huober, Andreas Schneeweiss, Andreas D Hartkopf, Volkmar Müller, Michael P Lux, Wolfgang Janni, Johannes Ettl, Erik Belleville, Marc Thill, Peter A Fasching and 9 more

Abstract read
In one paragraph

Article in Geburtshilfe und Frauenheilkunde, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Jens HuoberDepartment of Gynecology and Obstetrics, Ulm University Hospital, Ulm, Germany.
Andreas SchneeweissNational Center for Tumor Diseases, University Hospital and German Cancer Research Center, Heidelberg, Germany.
Andreas D HartkopfDepartment of Obstetrics and Gynecology, University of Tübingen, Tübingen, Germany.
Volkmar MüllerDepartment of Gynecology, Hamburg-Eppendorf University Medical Center, Hamburg, Germany.
Michael P LuxKlinik für Gynäkologie und Geburtshilfe, Frauenklinik St. Louise, Paderborn, St. Josefs-Krankenhaus, Salzkotten, Germany.
Wolfgang JanniDepartment of Gynecology and Obstetrics, Ulm University Hospital, Ulm, Germany.
Johannes EttlDepartment of Obstetrics and Gynecology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Erik BellevilleClinSol GmbH & Co KG, Würzburg, Germany.
Marc ThillAgaplesion Markus Krankenhaus, Department of Gynecology and Gynecological Oncology, Frankfurt, Germany.
Peter A FaschingErlangen University Hospital, Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
Hans-Christian KolbergDepartment of Gynecology and Obstetrics, Marienhospital Bottrop, Bottrop, Germany.
Carla E SchulmeyerErlangen University Hospital, Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
Manfred WelslauOnkologie Aschaffenburg, Aschaffenburg, Germany.
Friedrich OverkampOncoConsult Overkamp, Berlin, Germany.
Hans TeschOncology Practice at Bethanien Hospital Frankfurt, Frankfurt, Germany.
Tanja N FehmDepartment of Gynecology and Obstetrics, University Hospital Düsseldorf, Düsseldorf, Germany.
Diana LüftnerCharité University Hospital, Department of Hematology, Oncology and Tumour Immunology, Berlin, Germany.
Florian SchützDepartment of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany.
Achim WöckelDepartment of Gynecology and Obstetrics, University Hospital Würzburg, Würzburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of patients with early breast cancer has always been characterised by escalation by new therapies and de-escalation through identification of better treatment regimens or introduction of better tools to estimate prognosis. Efforts in some of these areas in the last few years have led to solid data. The results of the large studies of de-escalation through use of multi-gene tests are available, as are the results of some studies that investigated the new anti-HER2 substances T-DM1 and pertuzumab in the early treatment situation. Several large-scale studies examining the role of CDK4/6 inhibitors will soon be concluded so innovations can be anticipated in this area also. This review article will summarise and classify the results of the latest publications.

Indexed as

digital medicineearly breast cancerimmunotherapypreventionprognosistreatment

Identifiers

PMID33173238
PMCPMC7647721

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.