Evidence map›Paper›PMID 33173178›Full record

ArticlePediatric research2021

Risk factors for recurrent respiratory tract infection in preschool-aged children.

Bo Zhou, Wenquan Niu, Fangyu Liu, Yuan Yuan, Kundi Wang, Jing Zhang, Yunfeng Wang, Zhixin Zhang

Abstract read
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In one paragraph

Article in Pediatric research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  20. Beta-(1,3/1,6)-D-glucan fromFrontiers in pediatrics · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Bo Zhou *Graduate School, Beijing University of Chinese Medicine, Beijing, China.
Wenquan Niu *Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing, China.
Fangyu Liu *Graduate School, Beijing University of Chinese Medicine, Beijing, China.
Yuan Yuan *Graduate School, Beijing University of Chinese Medicine, Beijing, China.
Kundi WangDepartment of Pediatrics, China-Japan Friendship Hospital, Beijing, China.
Jing ZhangDepartment of Pediatrics, China-Japan Friendship Hospital, Beijing, China.
Yunfeng WangDepartment of Pediatrics, China-Japan Friendship Hospital, Beijing, China.
Zhixin ZhangInternational Medical Services, China-Japan Friendship Hospital, Beijing, China. zhangzhixin032@163.com.
China-Japan Friendship Hospital · CNBeijing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to identify potential risk factors for recurrent respiratory tract infection among Chinese preschool-aged children, and further to construct a nomogram prediction model.

methodsThis is a cross-sectional survey conducted in Beijing. Utilizing a stratified cluster random sampling strategy, a total of 7222 children from 20 kindergartens were enrolled. Data are analyzed by STATA software and R language.

resultsFive independent factors were identified to be significantly associated with recurrent respiratory tract infection risk overall and by pathogenic sites. The significant odds of recurrent respiratory tract infection was 8.31 (95% confidence interval [CI]: 5.69-12.12, P < 0.001), 2.31 (2.06-2.58, P < 0.001), 1.72 (1.48-1.99, P < 0.001), 1.24 (1.08-1.43, P = 0.002), and 1.19 (1.09-1.31, P < 0.001) for asthma, allergy, initial use of antibiotics <6 months, breastfeeding duration <6 months, and maternal body mass index, respectively. Besides the leading role played by asthma, allergy, initial use of antibiotics, and breastfeeding might exert a graded, dose-dependent effect on recurrent respiratory tract infection susceptibility.

conclusionsWe have identified five potential risk factors for the risk of recurrent respiratory tract infection from 7222 preschool-aged Chinese children. Notably, asthma plays a leading role, and allergy, initial use of antibiotics, and breastfeeding might exert a graded, dose-dependent effect on recurrent respiratory tract infection susceptibility. IMPACT: This is the first report of examining the joint contribution of multiple potential risk factors to recurrent respiratory tract infection among Chinese preschool-aged children. We have identified five potential risk factors for the risk of recurrent respiratory tract infection via analyzing survey data from 7222 preschool-aged Chinese children. Asthma plays a leading role, and allergy, initial use of antibiotics, and breastfeeding might exert a graded, dose-dependent effect on recurrent respiratory tract infection susceptibility.

Indexed as

AsthmaBreast FeedingChild, PreschoolChinaCross-Sectional StudiesFemaleHumansHypersensitivityMalePregnancyRecurrenceRespiratory Tract InfectionsRisk Factors

Identifiers

PMID33173178
OpenAlexW3098787602

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.