Evidence map›Paper›PMID 33173110›Full record

ArticleScientific reports2020

Proteomics reveals that quinoa bioester promotes replenishing effects in epidermal tissue.

Amanda C Camillo-Andrade, Marlon D M Santos, Juliana S G Fischer, Bruna B Swinka, Bruna Bosquetti, Desirée C Schuck, Marcia R Pincerati, Marcio Lorencini, Paulo C Carvalho

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amanda C Camillo-AndradeMaster Program in Industrial Biotechnology, Positivo University, R. Prof. Pedro Viriato Parigot de Souza, 5300, Curitiba, Paraná, Brazil.
Marlon D M SantosLaboratory for Structural and Computational Proteomics, Carlos Chagas Institute, Fiocruz - Paraná, R. Professor Algacyr Munhoz Mader 3775, Curitiba, PR, Brazil.
Juliana S G FischerLaboratory for Structural and Computational Proteomics, Carlos Chagas Institute, Fiocruz - Paraná, R. Professor Algacyr Munhoz Mader 3775, Curitiba, PR, Brazil.
Bruna B SwinkaGrupo Boticário, Research and Development Department, R. Alfredo Pinto, 198, Afonso Pena, São José Dos Pinhais, PR, Brazil.
Bruna BosquettiGrupo Boticário, Research and Development Department, R. Alfredo Pinto, 198, Afonso Pena, São José Dos Pinhais, PR, Brazil.
Desirée C SchuckGrupo Boticário, Research and Development Department, R. Alfredo Pinto, 198, Afonso Pena, São José Dos Pinhais, PR, Brazil.
Marcia R PinceratiMaster Program in Industrial Biotechnology, Positivo University, R. Prof. Pedro Viriato Parigot de Souza, 5300, Curitiba, Paraná, Brazil.
Marcio LorenciniGrupo Boticário, Research and Development Department, R. Alfredo Pinto, 198, Afonso Pena, São José Dos Pinhais, PR, Brazil. marciolo@grupoboticario.com.br.
Paulo C CarvalhoLaboratory for Structural and Computational Proteomics, Carlos Chagas Institute, Fiocruz - Paraná, R. Professor Algacyr Munhoz Mader 3775, Curitiba, PR, Brazil. paulo@pcarvalho.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The continuous search for natural products that attenuate age-related losses has increasingly gained notice; among them, those applicable for skin care have drawn significant attention. The bioester generated from the Chenopodium quinoa's oil is a natural-origin ingredient described to produce replenishing skin effects. With this as motivation, we used shotgun proteomics to study the effects of quinoa bioester on human reconstructed epidermis tridimensional cell cultures after 0, 3, 6, 12, 24, and 48 h of exposure. Our experimental setup employed reversed-phase nano-chromatography coupled online with an Orbitrap-XL and PatternLab for proteomics as the data analysis tool. Extracted ion chromatograms were obtained as surrogates for relative peptide quantitation. Our findings spotlight proteins with increased abundance, as compared to the untreated cell culture counterparts at the same timepoints, that were related to preventing premature aging, homeostasis, tissue regeneration, protection against ultraviolet radiation and oxidative damage.

Indexed as

Biological ProductsCells, CulturedChenopodium quinoaEpidermisEstersHumansMass SpectrometryPeptidesProteomicsBiological ProductsEstersPeptides

Identifiers

PMID33173110
PMCPMC7655866

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.