Evidence map›Paper›PMID 33172853›Full record

ArticleBJGP open2021

Pregabalin prescribing patterns in Australian general practice, 2012-2018: a cross-sectional study.

Andrea L Schaffer, Doreen Busingye, Kendal Chidwick, Jonathan Brett, Suzanne Blogg

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BJGP open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Andrea L SchafferCentre for Big Data Research in Health, University of New South Wales, Sydney, New South Wales, Australia andrea.schaffer@unsw.edu.au.ORCID http://orcid.org/0000-0002-3701-4997
Doreen BusingyeNPS Medicinewise, Strawberry Hills, New South Wales, Australia.
Kendal ChidwickNPS Medicinewise, Strawberry Hills, New South Wales, Australia.
Jonathan BrettCentre for Big Data Research in Health, University of New South Wales, Sydney, New South Wales, Australia.
Suzanne BloggNPS Medicinewise, Strawberry Hills, New South Wales, Australia.
Healthwise · USUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2013 pregabalin was subsidised by Australia's Pharmaceutical Benefits Scheme (PBS) for neuropathic pain. Since the subsidy, pregabalin prescribing has been increasing in Australia and so has related harm. There are concerns it is being prescribed for indications other than neuropathic pain, which have little evidence of efficacy.

aimTo describe pregabalin prescribing in Australian general practice. DESIGN &

settingA cross-sectional study of patients attending 445 general practice sites in the national MedicineInsight database from March 2012-February 2018.

methodThe following aspects were calculated: the proportion of prescriptions that were for pregabalin per year; the prevalence of pain conditions in patients prescribed pregabalin; and same-day prescribing of pregabalin with opioids or benzodiazepines.

resultsPrescribing increased from 13 per 10 000 to 104 per 10 000 prescriptions between 2012-2013 and 2017-2018. A total of 1 891 623 patients were identified of whom 114 123 (6.0%) were prescribed pregabalin; 49.7% (

Indexed as

epidemiologygabapentinoidsgeneral practiceneuralgianeuropathic painpregabalin

Identifiers

PMID33172853
PMCPMC7960512
OpenAlexW3103275507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.