ReviewMalaria journal2020
Reactive Case Detection (RACD) and foci investigation strategies in malaria control and elimination: a review.
Review in Malaria journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Equity gaps in neglected tropical disease research in Malaysia: a systematic review, 2014-2024.BMC public health · 2026Pooled it
- Systematic review of evidence for the impact and effectiveness of the 1-3-7 strategy for malaria elimination.Malaria journal · 2024Pooled it
- Malaria Control, Elimination, and Prevention as Components of Health Security: A Review.The American journal of tropical medicine and hygiene · 2022Pooled it
- A Systematic Review and Meta-Analysis of Malaria Test Positivity Outcomes and Programme Interventions in Low Transmission Settings in Southern Africa, 2000-2021.International journal of environmental research and public health · 2022Pooled it
- Asymptomatic parasitaemia in a malaria pre-elimination setting in the Putumayo area of the Ecuadorian Amazon basin.Malaria journal · 2025Article
- Malaria risk, treatment-seeking, and prevention in Northeastern India: clinic-based surveillance of persistent transmission.Malaria journal · 2025Article
- Assessment of a highly sensitive rapid diagnostic test for reactive case detection of Plasmodium Falciparum infections in Myanmar.Malaria journal · 2025Article
- First field evaluation of novel LDH- and HRP2-based rapid tests for Plasmodium vivax and Plasmodium falciparum malaria diagnosis.PLoS neglected tropical diseases · 2025Article
- Evaluating malaria reactive surveillance and response strategies in northeast Cambodia: a mixed-methods study.Malaria journal · 2025Article
- Implementation outcomes of 1-3-7 focus investigation for malaria in a low transmission setting in Southern Province, Zambia: A mixed methods study.PLOS global public health · 2025Article
- Implementation and fidelity of reactive surveillance and response strategies for malaria elimination: a systematic review and meta-analysis.BMJ public health · 2025Article
- Article
- Risk Factor Analysis of Cutaneous Leishmaniasis in Sri Lanka through a Nationwide Survey.The American journal of tropical medicine and hygiene · 2024Article
- Quantifying the impact of interventions against Plasmodium vivax: A model for country-specific use.Epidemics · 2024Article
- Supplementing routine hospital surveillance of malaria to capture excess mortality and epidemiological trends: a five-year observational study.Frontiers in malaria · 2024Article
- Successful elimination of falciparum malaria following the introduction of community-based health workers in Eastern Myanmar: A retrospective analysis.PLoS medicine · 2023Article
- How Real-Time Case-Based Malaria Surveillance Helps Zanzibar Get a Step Closer to Malaria Elimination: Description of Operational Platform and Resources.Global health, science and practice · 2023Article
- 1-3-7 surveillance and response approach in malaria elimination: China's practice and global adaptions.Malaria journal · 2023Review
- Reactive Case Detection Strategy for Malaria Control and Elimination: A 12 Year Systematic Review and Meta-Analysis from 25 Malaria-Endemic Countries.Tropical medicine and infectious disease · 2023Review
- Environmental Factors Linked to Reporting of Active Malaria Foci in Thailand.Tropical medicine and infectious disease · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundReactive case detection (RACD) and foci investigation are key strategies in malaria elimination and prevention of its re-establishment. They are a key part of surveillance that has been recommended by the World Health Organization (WHO) to be considered as a core intervention and as one of the three pillars of the Global Technical Strategy for Malaria 2016-2030.
methodsA search using the key words "Reactive Case Detection", "RACD", "RCD" and "Malaria" was carried out in PubMed, Scopus, Taylor and Francis online databases for studies published until 31st July 2019. The inclusion criteria for selection of articles for review included (1) how RACD is implemented in each country; (2) challenges faced in RACD implementation; (3) suggestions on how the effectiveness of RACD process can be improved.
results411 titles were identified, 41 full text articles were screened and 29 were found eligible for inclusion in the review. Published literature on RACD, and case and foci investigations has mostly assessed the process of the activity. Most studies have documented that the yield of positives in RACD has been highest in the index case's household and the immediate neighbourhood of the index case. Microscopy and RDTs are the common tests used in RACD. The guidelines for case and foci investigation, and RACD and PACD, are not universally adopted and are country-specific. Some of the limitations and challenges identified include lack of proper guidelines, logistic issues and problems with public compliance.
conclusionsAlthough there is no documented evidence that RACD is useful in malaria elimination settings, most authors have opined that RACD is necessary for malaria elimination. Lack of knowledge in the target populations, a target radius and how to carry out the RACD process is a major challenge in the decision-making process.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.