Evidence map›Paper›PMID 33172408›Full record

ArticleBMC nephrology2020

Exploring patient willingness to accept hepatitis C-infected kidneys for transplantation.

Gretchen C Edwards, Maren E Shipe, Lindsay Smith, Christianna Gamble, David Shaffer, Beatrice P Concepcion, Rachel Forbes

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Time to reconsider the role of donor hepatitis C status in the Kidney Donor Risk Index.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Article
  2. Association of donor hepatitis C virus infection status and risk of BK polyomavirus viremia after kidney transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Gretchen C EdwardsDepartment of General Surgery, Vanderbilt University Medical Center, Medical Center North, Suite CCC-4312, 1161 21st Avenue South, Nashville, TN, 37232-2730, USA. Gretchen.C.Edwards@vumc.org.ORCID 0000-0002-6312-6546
Maren E ShipeDepartment of General Surgery, Vanderbilt University Medical Center, Medical Center North, Suite CCC-4312, 1161 21st Avenue South, Nashville, TN, 37232-2730, USA.
Lindsay SmithVanderbilt University Medical Center Transplant Center, Nashville, USA.
Christianna GambleVanderbilt University Medical Center Transplant Center, Nashville, USA.
David ShafferDepartment of General Surgery, Division of Kidney and Pancreas Transplantation, Vanderbilt University Medical Center, Nashville, USA.
Beatrice P ConcepcionDepartment of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, USA.
Rachel ForbesDepartment of General Surgery, Division of Kidney and Pancreas Transplantation, Vanderbilt University Medical Center, Nashville, USA.
Vanderbilt University Medical Center · US

Funding

Learning Health System training program: PROgRESS--Patient/ pRactice Outcomes and Research in Effectiveness and Systems ScienceT32HS026122 · AHRQ · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GRIJALVA, CARLOS G, ROUMIE, CHRISTIANNE L. · 2018 to 2024
$3.5M
AHRQ HHS T32 HS026122
6 · The paper itself

Abstract

backgroundAs organs infected with Hepatitis C virus (HCV) provide an opportunity to expand the donor pool, the primary aim of this study is to explore patient willingness to accept a kidney from HCV-infected donors compared to other high-risk donors.

methodsAn anonymous, electronic survey was sent to all active kidney transplant waitlist patients at a single large volume transplant center. Patients were asked to respond to three hypothetical organ offers from the following: 1) HCV-infected donor 2) Donor with active intravenous drug use and 3) Donor with longstanding diabetes and hypertension.

resultsThe survey was sent to 435 patients of which 125 responded (29% response rate). While 86 out of 125 patients (69%) were willing to accept an HCV-infected kidney, only a minority of respondents were willing to accept a kidney from other high-risk donors. In contrast to other studies, by multivariable logistic regression, age and race were not associated with willingness to accept an HCV-infected kidney.

conclusionsIn this exploratory study, utilization of kidneys from HCV-infected donors to expand the donor pool appears to be an acceptable option to patients.

Indexed as

Donor SelectionHepatitis CKidney TransplantationPatient Acceptance of Health CareDiabetes MellitusFemaleHepacivirusHumansKidneyLogistic ModelsMaleMiddle AgedRenal DialysisSubstance Abuse, IntravenousSurveys and QuestionnairesWaiting ListsDeceased donor kidney transplantDisparitiesExpanded donor criteriaHepatitis CPHS-high risk

Identifiers

PMID33172408
PMCPMC7653701
OpenAlexW3101329553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.