Evidence map›Paper›PMID 33172215›Full record

ArticleMaterials (Basel, Switzerland)2020

Evaluation of Cytotoxicity and Antibacterial Activity of a New Class of Silver Citrate-Based Compounds as Endodontic Irrigants.

Luigi Generali, Carlo Bertoldi, Alessandro Bidossi, Clara Cassinelli, Marco Morra, Massimo Del Fabbro, Paolo Savadori, Nidambur Vasudev Ballal, Luciano Giardino

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Luigi GeneraliDepartment of Surgery, Medicine, Dentistry and Morphological Sciences with Transplant Surgery, Oncology and Regenerative Medicine Relevance (C.H.I.M.O.M.O.), University of Modena and Reggio Emilia, 41124 Modena, Italy.ORCID 0000-0003-3764-7046
Carlo BertoldiDepartment of Surgery, Medicine, Dentistry and Morphological Sciences with Transplant Surgery, Oncology and Regenerative Medicine Relevance (C.H.I.M.O.M.O.), University of Modena and Reggio Emilia, 41124 Modena, Italy.ORCID 0000-0001-9776-5138
Alessandro BidossiLaboratory of Clinical Chemistry and Microbiology, I.R.C.C.S. Orthopedic Institute Galeazzi, 20161 Milan, Italy.
Clara CassinelliNobil Bio Ricerche srl, Via Valcastellana 26, 14037 Portacomaro, Italy.
Marco MorraNobil Bio Ricerche srl, Via Valcastellana 26, 14037 Portacomaro, Italy.
Massimo Del FabbroDepartment of Biomedical, Surgical and Dental Sciences, University of Milano, 20122 Milan, Italy.ORCID 0000-0001-7144-0984
Paolo SavadoriI.R.C.C.S. Orthopedic Institute Galeazzi, 20161 Milan, Italy.
Nidambur Vasudev BallalDepartment of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, 576104 Karnataka, India.ORCID 0000-0002-2208-9443
Luciano GiardinoFreelance Researcher, 88900 Crotone, Italy.ORCID 0000-0003-2970-6683
Istituto Ortopedico Galeazzi · ITUniversity of Modena and Reggio Emilia · ITIstituto S.Anna Crotone · ITManipal Academy of Higher Education · INUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, the cytotoxicity and the antimicrobial activity of two silver citrate-based irrigant solutions were investigated. Cytotoxicity of various concentrations (0.25%, 0.5%, 1%, 2.5%, 5%) of both solutions (BioAKT and BioAKT Endo) was assessed on L-929 mouse fibroblasts using the MTT assay. For the quantitative analysis of components, an infrared (I.R.) spectroscopy was performed. The minimum inhibitory and minimal bactericidal concentrations (M.I.C. and M.B.C., respectively) were ascertained on

Indexed as

biofilmconfocal laser scanning microscopyendodontic irrigantEnterococcus faecalisM.T.T. assaysilver citrate

Identifiers

PMID33172215
PMCPMC7664443
OpenAlexW3096590470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.