ArticleFoods (Basel, Switzerland)2020
Pomegranate (
Article in Foods (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
- Condition-dependent effects of phenolic Copigments on anthocyanin stability in Chinese bayberry juice: An HPLC-degradation kinetic study.Food chemistry: X · 2026Article
- Article
- Structure-effect relationship of phenolic compounds onCurrent research in food science · 2026Article
- Photoprotective, Antioxidant and Anti-Inflammatory Effects of AgedFood science & nutrition · 2025Article
- Fourier Spectral Deconvolution to Describe Behaviors of pH-Dependent Monomeric and Self-Associated Anthocyanin Species.Journal of chemical information and modeling · 2025Article
- Antioxidant Activity of Anthocyanins and Anthocyanidins: A Critical Review.International journal of molecular sciences · 2024Review
- Antibacterial Effect of Pomegranate Juice onFoods (Basel, Switzerland) · 2023Article
- The Impact ofAntioxidants (Basel, Switzerland) · 2023Review
- Mexican Native Black Bean Anthocyanin-Rich Extracts Modulate Biological Markers Associated with Inflammation.Pharmaceuticals (Basel, Switzerland) · 2023Article
- The effect of oral use of concentrated pomegranate juice by mothers on hyperbilirubinemia in neonates under phototherapy: A randomized clinical trial.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2023Article
- Rich in Phenolics-Strong Antioxidant Fruit? Comparative Study of 25 Strawberry Cultivars.Plants (Basel, Switzerland) · 2022Article
- Article
- Photoprotective Agents Obtained from Aromatic Plants Grown in Colombia: Total Phenolic Content, Antioxidant Activity, and Assessment of Cytotoxic Potential in Cancer Cell Lines ofPlants (Basel, Switzerland) · 2022Article
- Bioactive Phenolic Compounds from Lingonberry (Antioxidants (Basel, Switzerland) · 2022Article
- Tropical Fruits and Their Co-Products as Bioactive Compounds and Their Health Effects: A Review.Foods (Basel, Switzerland) · 2021Review
- Elucidation of Volatiles, Anthocyanins, Antioxidant and Sensory Properties ofFoods (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Secondary plant metabolites, e.g., polyphenols, are widely known as health-improving compounds that occur in natural functional foods such as pomegranates. While extracts generated from these fruits inhibit oxidative stress, the allocation of these effects to the different subgroups of substances, e.g., anthocyanins, "copigments" (polyphenols without anthocyanins), or polymeric compounds, is still unknown. Therefore, in the present study, polyphenols from pomegranate juice were extracted and separated into an anthocyanin and copigment fraction using adsorptive membrane chromatography. Phenolic compounds were determined by high performance liquid chromatography with photodiode array (HPLC-PDA) detection and HPLC-PDA electrospray ionization tandem mass spectrometry (HPLC-PDA-ESI-MS/MS), while the free radical scavenging activity of the pomegranate XAD‑7 extract and its fractions was evaluated by the Trolox equivalent antioxidant capacity (TEAC) assay and electron spin resonance (ESR) spectroscopy. Compared to juice, the total phenolic content and free radical scavenging potential was significantly higher in the pomegranate XAD-7 extract and its fractions. In comparison to the anthocyanin and copigment fraction, pomegranate XAD-7 extract showed the highest radical scavenging activity against galvinoxyl and DPPH radicals. Moreover, the enriched XAD-7 extract and its fractions were able to protect human hepatocellular HepG2 cells against oxidative stress induced by hydrogen peroxide. Overall, these results indicated that anthocyanins and copigments act together in reducing oxidative stress.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.