Evidence map›Paper›PMID 33172098›Full record

ReviewBiosensors2020

Interfacing DNA with Gold Nanoparticles for Heavy Metal Detection.

Zhiyu He, Huiling Yin, Chia-Chen Chang, Guoqing Wang, Xingguo Liang

Open access · goldAbstract readReview
In one paragraph

Review in Biosensors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Zhiyu HeCollege of Food Science and Engineering, Ocean University of China, Qingdao 266003, China.
Huiling YinCollege of Food Science and Engineering, Ocean University of China, Qingdao 266003, China.
Chia-Chen ChangDepartment of Medical Biotechnology and Laboratory Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0001-5466-4724
Guoqing WangCollege of Food Science and Engineering, Ocean University of China, Qingdao 266003, China.ORCID 0000-0003-0148-4417
Xingguo LiangCollege of Food Science and Engineering, Ocean University of China, Qingdao 266003, China.ORCID 0000-0001-7778-4593
Ocean University of China · CNQingdao National Laboratory for Marine Science and Technology · CNChang Gung University · TW

Funding

Shandong Provincial Science Foundation ZR2019QC011Shandong Provincial Soft Science Research Program 2019RKE29001
6 · The paper itself

Abstract

The contamination of heavy metals (e.g., Hg, Pb, Cd and As) poses great risks to the environment and human health. Rapid and simple detection of heavy metals of considerable toxicity in low concentration levels is an important task in biological and environmental analysis. Among the many convenient detection methods for heavy metals, DNA-inspired gold nanoparticles (DNA-AuNPs) have become a well-established approach, in which assembly/disassembly of AuNPs is used for colorimetric signaling of the recognition event between DNA and target heavy metals at the AuNP interface. This review focuses on the recent efforts of employing DNA to manipulate the interfacial properties of AuNPs, as well as the major advances in the colorimetric detection of heavy metals. Beginning with the introduction of the fundamental aspects of DNA and AuNPs, three main strategies of constructing DNA-AuNPs with DNA binding-responsive interface are discussed, namely, crosslinking, electrostatic interaction and base pair stacking. Then, recent achievements in colorimetric biosensing of heavy metals based on manipulation of the interface of DNA-AuNPs are surveyed and compared. Finally, perspectives on challenges and opportunities for future research in this field are provided.

Indexed as

Biosensing TechniquesColorimetryDNAGoldHumansLimit of DetectionMercuryMetal NanoparticlesMetals, HeavyDNAGoldMercuryMetals, HeavybiosensingDNAgold nanoparticlesheavy metalinterface

Identifiers

PMID33172098
PMCPMC7694790
OpenAlexW3097453295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.