Evidence map›Paper›PMID 33171981›Full record

ArticleInternational journal of molecular sciences2020

The Cytogenomic "Theory of Everything": Chromohelkosis May Underlie Chromosomal Instability and Mosaicism in Disease and Aging.

Ivan Y Iourov, Svetlana G Vorsanova, Yuri B Yurov, Maria A Zelenova, Oxana S Kurinnaia, Kirill S Vasin, Sergei I Kutsev

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Chromoanagenesis and Beyond: Catastrophic Events Shaping the Genome.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  2. Tracking Karyotype Changes in Treatment-Induced Drug-Resistant Evolution.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  3. Quantitative FISHing: Implications for Chromosomal Analysis.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  4. Review
  5. Cytogenomic epileptology.Molecular cytogenetics · 2023
    Review
  6. Somatic mosaicism in the diseased brain.Molecular cytogenetics · 2022
    Review
  7. Svetlana G. Vorsanova (1945-2021).Molecular cytogenetics · 2022
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ivan Y IourovMental Health Research Center, 117152 Moscow, Russia.
Svetlana G VorsanovaMental Health Research Center, 117152 Moscow, Russia.
Yuri B YurovMental Health Research Center, 117152 Moscow, Russia.
Maria A ZelenovaMental Health Research Center, 117152 Moscow, Russia.
Oxana S KurinnaiaMental Health Research Center, 117152 Moscow, Russia.
Kirill S VasinMental Health Research Center, 117152 Moscow, Russia.
Sergei I KutsevResearch Centre for Medical Genetics, 115522 Moscow, Russia.

Funding

RFBR and CITMA 18-515-34005Russian Ministry of Health AAAA-A18-118051590122-7Russian Ministry of Science and Higher Education AAAA-A19-119040490101-6
6 · The paper itself

Abstract

Mechanisms for somatic chromosomal mosaicism (SCM) and chromosomal instability (CIN) are not completely understood. During molecular karyotyping and bioinformatic analyses of children with neurodevelopmental disorders and congenital malformations (

Indexed as

AgingAneuploidyCentromereChildChromosomal InstabilityChromosome AberrationsChromosome DisordersChromosomesCongenital AbnormalitiesDiploidyDiseaseDNA Copy Number VariationsFemaleGenomeHumansKaryotypingaginganeuploidychromosomal imbalanceschromosomal mosaicismchromosomechromosome instabilitycopy number variationscytogenomicsdiseasepathways

Identifiers

PMID33171981
PMCPMC7664247

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.