Evidence map›Paper›PMID 33171819›Full record

ArticleCancers2020

Orally Administered 5-aminolevulinic Acid for Isolation and Characterization of Circulating Tumor-Derived Extracellular Vesicles in Glioblastoma Patients.

Sybren L N Maas, Thomas S van Solinge, Rosalie Schnoor, Anudeep Yekula, Joeky T Senders, Jeroen de Vrij, Pierre Robe, Bob S Carter, Leonora Balaj, Ger J A Arkesteijn and 2 more

Abstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Liquid biopsy: early and accurate diagnosis of brain tumor.Journal of cancer research and clinical oncology · 2022
    Review
  8. Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sybren L N MaasDepartment of Neurosurgery, UMC Utrecht Brain Center, Utrecht University, 3584 CX Utrecht, The Netherlands.
Thomas S van SolingeDepartments of Neurology and Radiology, Massachusetts General Hospital, and NeuroDiscovery Center, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0003-3762-3618
Rosalie SchnoorDepartment of Neurosurgery, UMC Utrecht Brain Center, Utrecht University, 3584 CX Utrecht, The Netherlands.
Anudeep YekulaDepartment of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-0713-0292
Joeky T SendersDepartment of Neurosurgery, UMC Utrecht Brain Center, Utrecht University, 3584 CX Utrecht, The Netherlands.
Jeroen de VrijDepartment of Neurosurgery, Erasmus MC, 3015 GD Rotterdam, The Netherlands.
Pierre RobeDepartment of Neurosurgery, University Medical Centre Utrecht, 3584 CX Utrecht, The Netherlands.ORCID 0000-0001-7845-6196
Bob S CarterDepartment of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Leonora BalajDepartment of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0003-0931-9715
Ger J A ArkesteijnDepartment of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CX Utrecht, The Netherlands.ORCID 0000-0001-7739-582X
Esther N M Nolte-'t HoenDepartment of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CX Utrecht, The Netherlands.
Marike L D BroekmanDepartments of Neurology and Radiology, Massachusetts General Hospital, and NeuroDiscovery Center, Harvard Medical School, Boston, MA 02114, USA.

Funding

The power of extracellular vesicles in glioblastomaR35CA232103 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI BREAKEFIELD, XANDRA OWENS · 2018 to 2024
$6.9M
Liquid Biopsy for treatment stratification of IDH1.R132H and EGFRvIII mutant gliomasU01CA230697 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CARTER, BOB S, SKOG, JOHAN · 2018 to 2022
$4.0M
Imaging and Liquid Biopsy for Glioma Diagnosis and Treatment MonitoringR01CA239078 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI BALAJ, LEONORA, LEE, HAKHO · 2020 to 2024
$3.1M
Bekker-la Bastide Fund -Bontius Stichting -Foundation Vrijvrouwe van Renswoude -NCI NIH HHS R01 CA239078NCI NIH HHS R35 CA232103NCI NIH HHS U01 CA230697Nijbakker-Morra Fund -
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

5 aminolevulinic acidextracellular vesiclesglioblastomahigh-resolution flow cytometryprotoporphyrin IX

Identifiers

PMID33171819
PMCPMC7695169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.