Evidence map›Paper›PMID 33171802›Full record

ReviewMolecules (Basel, Switzerland)2020

Nanomaterials for Cardiac Tissue Engineering.

Devang R Amin, Eric Sink, Suguna P Narayan, Mostafa Abdel-Hafiz, Luisa Mestroni, Brisa Peña

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 63 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Bioprinting of Cardiac Tissue in Space: Where Are We?Advanced healthcare materials · 2023
    Article
  8. Review
  9. Review
  10. Nanomedicines for cardiovascular disease.Nature cardiovascular research · 2023
    Review
  11. Review
  12. Review
  13. Article
  14. Future Prospects for Clinical Applications of Nanocarbons Focusing on Carbon Nanotubes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Devang R AminDepartment of Internal Medicine, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USA.
Eric SinkDepartment of Internal Medicine, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USA.
Suguna P NarayanDepartment of Pathology, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USA.
Mostafa Abdel-HafizDepartment of Bioengineering, University of Colorado Denver, Anschutz Medical Campus, 12705 E. Montview Avenue, Suite 100, Aurora, CO 80045, USA.
Luisa MestroniCardiovascular Institute, University of Colorado Anschutz Medical Campus, 12700 E. 19th Avenue, Aurora, CO 80045, USA.ORCID 0000-0003-1116-2286
Brisa PeñaDepartment of Bioengineering, University of Colorado Denver, Anschutz Medical Campus, 12705 E. Montview Avenue, Suite 100, Aurora, CO 80045, USA.ORCID 0000-0003-4224-6626
University of Colorado Anschutz Medical Campus · USUniversity of Colorado Denver · US

Funding

Cardiomyocyte phenotype and mechanotransduction in Filamin C gene variants causing arrhythmogenic cardiomyopathyR01HL147064 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI MESTRONI, LUISA, TAYLOR, MATTHEW R · 2020 to 2023
$2.1M
Injectable Carbon Nanotube-Functionalized Hydrogel for miRNA DeliveryK25HL148386 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI PENA CASTELLANOS, BRISA MARISOL · 2020 to 2024
$891k
NHLBI NIH HHS K25 HL148386NIH HHS K25HL148386NIH HHS R01HL147064
6 · The paper itself

Abstract

End stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and carbon nanotubes (CNTs) present unique properties that are beneficial for cardiac tissue engineering approaches. In particular, these nanomaterials can modulate electrical conductivity, hardness, and roughness of bulk materials to improve tissue functionality. Moreover, they can deliver bioactive cargo to affect cell phenotypes. This review covers recent advances in the use of nanomaterials for cardiac tissue engineering.

Indexed as

AnimalsAnimals, NewbornBiocompatible MaterialsElectric ConductivityFerric CompoundsGoldHeartHumansMetal NanoparticlesMiceMicroRNAsMyocytes, CardiacNanostructuresNanotechnologyNanotubes, CarbonPhenotypeBiocompatible MaterialsFerric Compoundsferric oxideGoldMicroRNAsNanotubes, CarbonPolymerscarbon nanotubescardiac tissue engineeringcardiomyocyte regenerationgold nanorodsnanoparticles

Identifiers

PMID33171802
PMCPMC7664640
OpenAlexW3096276519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.