ReviewJournal of clinical medicine2020
The Role of Foot-Loading Factors and Their Associations with Ulcer Development and Ulcer Healing in People with Diabetes: A Systematic Review.
Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Accuracy of Foot Pressure Measurement on Predicting the Development of Foot Ulcer in Patients with Diabetes: A Systematic Review and Meta-Analysis.Journal of diabetes science and technology · 2023Pooled it
- Weight-bearing physical activity in people with diabetes-related foot disease: A systematic review.Diabetes/metabolism research and reviews · 2022Pooled it
- Australian guideline on prevention of foot ulceration: part of the 2021 Australian evidence-based guidelines for diabetes-related foot disease.Journal of foot and ankle research · 2022Guideline
- Clinical and Biomechanical Predictors of Forefoot Plantar Pressure in Individuals with Type 2 Diabetes and Peripheral Neuropathy.Medicina (Kaunas, Lithuania) · 2026Trial
- Effect of flexor tendon tenotomy of the diabetic hammertoe on plantar pressure: a randomized controlled trial.BMJ open diabetes research & care · 2024Trial
- Effectiveness of at-home skin temperature monitoring in reducing the incidence of foot ulcer recurrence in people with diabetes: a multicenter randomized controlled trial (DIATEMP).BMJ open diabetes research & care · 2021Trial
- Review
- One Shoe Doesn't Fit All: A Contextual Approach to Therapeutic Footwear for People at Risk of Diabetes-Related Foot Ulceration.Journal of foot and ankle research · 2026Review
- 5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes: Standards of Care in Diabetes-2026.Diabetes care · 2026Review
- Precision nutrition in diabetic foot ulcers: multimodal artificial intelligence for personalized metabolic management.Frontiers in nutrition · 2026Review
- The predictive value of cumulative plantar tissue stress on future plantar foot ulceration in people with diabetes-A 12-month prospective observational study.Diabetic medicine : a journal of the British Diabetic Association · 2025Observational
- SmartBoot: Real-Time Monitoring of Patient Activity via Remote Edge Computing Technologies.Sensors (Basel, Switzerland) · 2025Article
- Exploring Physical Activity in Individuals With Type 2 Diabetes Mellitus and Lower Limb Complications: A Scoping Review.Endocrinology, diabetes & metabolism · 2025Article
- Prevalence and predictors of infected diabetic foot ulcers (DFU) and DFU-related osteomyelitis amongst industrial workers wearing occupational safety footwear.Scientific reports · 2025Observational
- 5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes: Standards of Care in Diabetes-2025.Diabetes care · 2025Review
- Adherence to wearing prescribed footwear in people at risk of diabetes-related foot ulcers.Journal of foot and ankle research · 2024Article
- Foot offloading associated with carbon fiber orthosis use: A pilot study.Gait & posture · 2024Article
- Article
- A scientometrics analysis and visualisation of diabetic foot research from 1955 to 2022.International wound journal · 2023Article
- Personalized Offloading Treatments for Healing Plantar Diabetic Foot Ulcers.Journal of diabetes science and technology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
We aimed to comprehensively and systematically review studies associating key foot-loading factors (i.e., plantar pressure, weight-bearing activity, adherence or a combination thereof) with ulcer development and ulcer healing in people with diabetes. A systematic literature search was performed in PubMed and EMBASE. We included studies if barefoot or in-shoe plantar pressure, weight-bearing activity or footwear or device adherence was measured and associated with either ulcer development or ulcer healing in people with diabetes. Out of 1954 records, 36 studies were included and qualitatively analyzed. We found low to moderate quality evidence that lower barefoot plantar pressure and higher footwear and device adherence associate with lower risk of ulcer development and shorter healing times. For the other foot-loading factors, we found low quality evidence with limited or contradictory results. For combined measures of foot-loading factors, we found low quality evidence suggesting that lower cumulative plantar tissue stress is associated with lower risk of ulcer development and higher ulcer healing incidence. We conclude that evidence for barefoot plantar pressure and adherence in association with ulcer outcome is present, but is limited for the other foot-loading factors. More comprehensive investigation in particularly the combination of foot-loading factors may improve the evidence and targeting preventative treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.