Evidence map›Paper›PMID 33171665›Full record

ReviewMolecules (Basel, Switzerland)2020

Daylight Photodynamic Therapy: An Update.

Chaw-Ning Lee, Rosie Hsu, Hsuan Chen, Tak-Wah Wong

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 1 synthesis or guideline pooled it, 128 citations in OpenAlex.

  1. Pooled it
  2. Simulated daylight vs. conventional PDT for clinical superficial BCC: A randomized controlled trial.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Photodynamic Therapy in Dermatology.International journal of molecular sciences · 2026
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Daylight photodynamic therapy in nonmelanoma skin cancers and photorejuvenation.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Chaw-Ning LeeDepartment of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.ORCID 0000-0002-0848-0657
Rosie HsuDepartment of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.
Hsuan ChenDepartment of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.
Tak-Wah WongDepartment of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.
National Cheng Kung University Hospital · TW

Funding

Ministry of Education the Center of Applied Nanomedicine, National Cheng Kung University from the Featured Areas Research Center Program within the framework of the Higher Education Sprout ProjectMinistry of Science and Technology, Taiwan MOST 109-2327-B-006-005National Cheng Kung University B108-K102National Cheng Kung University Hospital NCKUH-10902032
6 · The paper itself

Abstract

Daylight photodynamic therapy (dPDT) uses sunlight as a light source to treat superficial skin cancer. Using sunlight as a therapeutic device has been present for centuries, forming the basis of photodynamic therapy in the 20th century. Compared to conventional PDT, dPDT can be a less painful, more convenient and an effective alternative. The first clinical uses of dPDT on skin cancers began in Copenhagen in 2008. Currently, aminolevulinic acid-mediated dPDT has been approved to treat actinic keratosis patients in Europe. In this review article, we introduce the history and mechanism of dPDT and focus on the pros and cons of dPDT in treating superficial skin cancers. The future applications of dPDT on other skin diseases are expected to expand as conventional PDT evolves.

Indexed as

Aminolevulinic AcidAnimalsAntineoplastic AgentsBasal Cell CarcinomaBowen's DiseaseCheilitisEuropeGlucoseGlutamineHumansKeratosis, ActinicPhotochemotherapyPhotosensitizing AgentsPorphyrinsRadiation ExposureSunlightAminolevulinic AcidAntineoplastic AgentsGlucoseGlutaminePhotosensitizing AgentsPorphyrinsactinic keratosisaminolevulinic aciddaylighthistorynonmelanoma skin cancerphotodynamic therapy

Identifiers

PMID33171665
PMCPMC7664668
OpenAlexW3099575697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.