ArticleDiagnostics (Basel, Switzerland)2020
Assessment of Therapeutic Response in Pyogenic Vertebral Osteomyelitis Using
Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Assessment of Therapeutic Responses Using a Deep Neural Network Based onMedicina (Kaunas, Lithuania) · 2022Trial
- Candida auris candidemia, septic arthritis, and vertebral osteomyelitis requiring dual antifungal therapy: a case report.Infection · 2026Article
- Efficacy of Additional Surgical Decompression on Functional Outcome in Pyogenic Spinal Epidural Abscess With No Neurological Deficit.Korean journal of neurotrauma · 2024Article
- The routine clinical use of fluorodeoxyglucose PET/CT to confirm treatment response in pyogenic spine infection.Skeletal radiology · 2024Article
- Analysis of Clinical Factors Associated with Medical Burden and Functional Status in Pyogenic Spine Infection.Journal of clinical medicine · 2023Article
- Validity of Clinical Assessment Using Clinical Symptoms and C-Reactive Protein for Therapeutic Response in Pyogenic Vertebral Osteomyelitis: Analysis Based onMedicina (Kaunas, Lithuania) · 2021Article
- Clinical and Radiological Features Predicting Intervertebral Autofusion after Successful Antibiotic Therapy in Pyogenic Vertebral Osteomyelitis.Diagnostics (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
purposeThere is still no definite method to determine therapeutic response in pyogenic vertebral osteomyelitis (PVO). We analyzed the value of
methodsThis retrospective study included 53 patients (32 men and 21 women) with lumbar PVO. The results of clinical assessments for therapeutic response were divided into "Cured" (group C) and "Non-cured" (group NC). The differences in clinical and radiological features of PVO lesions between the two groups were analyzed using clinical data and simultaneous FDG-PET/magnetic resonance imaging (MRI) obtained at each clinical assessment.
resultsClinical assessments and FDG-PET/MRIs were performed at 41.89 ± 16.08 (21-91) days of parenteral antibiotic therapy. There were 39 patients in group C and 14 in group NC. Diagnostic accuracies (DAs) of FDG uptake intensity-based interpretation and C-reactive protein (CRP) for residual PVO were as follows (
conclusionThe interpretations of intensity and distribution of FDG uptake on FDG-PET are useful for detecting residual PVO in the assessment of therapeutic response of PVO. The combination of FDG-PET and CRP is expected to increase DA for detecting residual PVO.
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