Evidence map›Paper›PMID 33171617›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Quantitative Evaluation of the Echo Intensity of Paraneural Area and Myofascial Structure around Median Nerve in Carpal Tunnel Syndrome.

Chenglei Fan, Caterina Fede, Carmelo Pirri, Diego Guidolin, Carlo Biz, Veronica Macchi, Raffaele De Caro, Carla Stecco

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Ultrasound Imaging of Brachial and Antebrachial Fasciae.Diagnostics (Basel, Switzerland) · 2021
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Chenglei FanDepartment of Neurosciences, Institute of Human Anatomy, University of Padua, 35121 Padua, Italy.ORCID 0000-0002-1129-0379
Caterina FedeDepartment of Neurosciences, Institute of Human Anatomy, University of Padua, 35121 Padua, Italy.ORCID 0000-0002-4372-7889
Carmelo PirriDepartment of Neurosciences, Institute of Human Anatomy, University of Padua, 35121 Padua, Italy.ORCID 0000-0002-0119-6549
Diego GuidolinDepartment of Neurosciences, Institute of Human Anatomy, University of Padua, 35121 Padua, Italy.ORCID 0000-0003-2133-3552
Carlo BizDepartment of Surgery, Oncology and Gastroenterology, Orthopedic Clinic, University of Padua, 35128 Padua, Italy.ORCID 0000-0001-8517-0057
Veronica MacchiDepartment of Neurosciences, Institute of Human Anatomy, University of Padua, 35121 Padua, Italy.ORCID 0000-0003-2335-6897
Raffaele De CaroDepartment of Neurosciences, Institute of Human Anatomy, University of Padua, 35121 Padua, Italy.ORCID 0000-0002-2307-0277
Carla SteccoDepartment of Neurosciences, Institute of Human Anatomy, University of Padua, 35121 Padua, Italy.ORCID 0000-0002-8767-4555
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate whether the echo intensity (EI) of the paraneural area (PA), the median nerve (MN) at the carpal tunnel, the EI of the myofascial structure (MS) around MN, the 'PA and MN' at the mid-forearm, and the MN transversal displacement at both sites differs between persons with carpal tunnel syndrome (CTS) and control subjects.

methodsIn total, 16 CTS patients and 16 controls, age- and gender-matched, were recruited. Cross-sectional ultrasound images of MN were obtained to evaluate the EI of the PA, the MN at carpal tunnel, the EI of MS, and the 'PA and MN' at the mid-forearm in a natural position, then images were taken after a whole-hand grasp movement, to evaluate MN transversal displacement. Inter-rater and intra-rater reliability in control, and differences in the EI and MN displacement between CTS and control, were analyzed. In addition, the correlations between ultrasound parameters and MN displacement were evaluated.

resultsThe quantitative EI of PA, MN, EI of MS, 'PA and MN' had high inter-rater and intra-rater reliability in the control. The EI of PA, MS and 'PA and MN' were significantly higher in CTS subjects (

conclusionsThe higher EI of PA and MS around MN in CTS may indicate greater fibrosis along the course of MN, reducing fascial adaptability, influencing the synergy and coordination of the MS, and increasing the shear stress between MS and MN, and it may further increase the abnormal pressure on the MN not only at the carpal tunnel, but also at the mid-forearm. These results may partly explain the role of PA and MS in CTS pathogenesis.

Indexed as

carpal tunnel syndromeecho intensitymedian nervemyofascial structureparaneural areaultrasound

Identifiers

PMID33171617
PMCPMC7695137
OpenAlexW3099804550

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.