Evidence map›Paper›PMID 33170957›Full record

ArticleJournal of the American Geriatrics Society2021

Guardianship and End-of-Life Care for Veterans with Dementia in Nursing Homes.

Andrew B Cohen, Ling Han, John R OʼLeary, Terri R Fried

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Guardianship: A medicolegal review for clinicians.Journal of the American Geriatrics Society · 2022
    Article
  4. End-of-Life Care for Persons Under Guardianship.Journal of pain and symptom management · 2021
    Article
  5. We Need a Paradigm Shift Around End-of-Life Decision Making.Journal of the American Geriatrics Society · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Andrew B CohenDepartment of Medicine, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0001-9161-8436
Ling HanDepartment of Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
John R OʼLearyDepartment of Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Terri R FriedDepartment of Medicine, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0001-8083-8265
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Denise Esserman · 2002 to 2026
$37.9M
Yale Training Program in Geriatric Clinical Epidemiology and Aging-Related ResearchT32AG019134 · NIA · YALE UNIVERSITY · PI Terri R. Fried · 2001 to 2026
$7.5M
Dementia and Decision-Making for Older Adults without SurrogatesK76AG059987 · NIA · YALE UNIVERSITY · PI COHEN, ANDREW B · 2018 to 2022
$1.2M
Guardianship and Medical Decision Making for the Unbefriended ElderlyR03AG053278 · NIA · YALE UNIVERSITY · PI COHEN, ANDREW B · 2016 to 2017
$251k
NCATS NIH HHS UL1 TR001863NIA NIH HHS K76 AG059987NIA NIH HHS K76AG059987NIA NIH HHS P30 AG021342NIA NIH HHS P30AG21342NIA NIH HHS R03 AG053278NIA NIH HHS R03AG053278NIA NIH HHS T32 AG019134
6 · The paper itself

Abstract

BACKGROUND/

objectivesExperts have suggested that patients represented by professional guardians receive higher intensity end-of-life treatment than other patients, but there is little corresponding empirical data.

designRetrospective cohort study. SETTING AND

participantsAmong veterans aged 65 and older who died from 2011 to 2013, we used Minimum Data Set assessments to identify those who were nursing home residents and had moderately severe or severe dementia. We applied methods developed in prior work to determine which of these veterans had professional guardians. Decedent veterans with professional guardians were matched to decedent veterans without guardians in a 1:4 ratio, according to age, sex, race, dementia severity, and nursing facility type (VA based vs non-VA). MEASUREMENTS: Our primary outcome was intensive care unit (ICU) admission in the last 30 days of life. Secondary outcomes included mechanical ventilation and cardiopulmonary resuscitation in the last 30 days of life, feeding tube placement in the last 90 days of life, three or more nursing home-to-hospital transfers in the last 90 days of life, and in-hospital death.

resultsICU admission was more common among patients with professional guardians than matched controls (17.5% vs 13.7%), but the difference was not statistically significant (adjusted odds ratio = 1.33; 95% confidence interval = .89-1.99). There were no significant differences in receipt of any other treatment; nor was there a consistent pattern. Mechanical ventilation and cardiopulmonary resuscitation were more common among patients with professional guardians, and feeding tube placement, three or more end-of-life hospitalizations, and in-hospital death were more common among matched controls.

conclusionRates of high-intensity treatment were similar whether or not a nursing home resident with dementia was represented by a professional guardian. This is in part because high-intensity treatment occurred more frequently than expected among patients without guardians.

Indexed as

Critical CareDementiaNursing HomesTerminal CareAgedFemaleHospital MortalityHumansIntensive Care UnitsLegal GuardiansMalePatient TransferRetrospective StudiesSeverity of Illness IndexThird-Party ConsentUnited Statescourt-appointed guardiansdementiaend-of-life carenursing homessurrogate decision-making

Identifiers

PMID33170957
PMCPMC7902349
OpenAlexW3105769393

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.