ArticleEsophagus : official journal of the Japan Esophageal Society2021
Modified geriatric nutrition risk index as a prognostic predictor of esophageal cancer.
Article in Esophagus : official journal of the Japan Esophageal Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- C-Reactive Protein and C-Reactive Protein-Based Scores to Predict Survival in Esophageal and Junctional Adenocarcinoma: Systematic Review and Meta-Analysis.Annals of surgical oncology · 2022Pooled it
- Prognostic Value of Geriatric Nutritional Risk Index in Esophageal Carcinoma: A Systematic Review and Meta-Analysis.Frontiers in nutrition · 2022Pooled it
- Integration of inflammatory and nutritional biomarkers with machine learning enhances prediction of progesterone response in fertility-preserving endometrial carcinoma management.Translational oncology · 2026Article
- Article
- Modified geriatric nutritional risk index: a high-sensitivity marker with L-shaped association for sarcopenia in hospitalized older adults.Frontiers in nutrition · 2025Article
- Prognostic importance of modified geriatric nutritional risk index in oral cavity squamous cell carcinoma.Scientific reports · 2024Article
- Molecular Targets and Mechanisms of Hedyotis diffusa Willd. for Esophageal Adenocarcinoma Treatment Based on Network Pharmacology and Weighted Gene Co-expression Network Analysis.Current drug targets · 2024Article
- A large-scale study integrating nutritional indicators and clinicopathological parameters to evaluate prognosis, follow-up, and postoperative chemotherapy decisions in rectal cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Clinical significance of postoperative subcutaneous emphysema after video-assisted thoracoscopic surgery for esophageal cancer.Surgical endoscopy · 2023Article
- Construction a new nomogram prognostic model for predicting overall survival after radical resection of esophageal squamous cancer.Frontiers in oncology · 2023Article
- Association of geriatric nutritional risk index with all-cause hospital mortality among elderly patients in intensive care unit.Frontiers in nutrition · 2023Article
- A novel inflammation-nutrition biomarker score for predicting prognosis of patients with cancer: results from a multicenter study.BMC cancer · 2022Article
- The advanced lung cancer inflammation index is the optimal inflammatory biomarker of overall survival in patients with lung cancer.Journal of cachexia, sarcopenia and muscle · 2022Article
- Modified geriatric nutritional risk index in patients with pancreatic cancer: a propensity score-matched analysis.BMC cancer · 2022Article
- Management of elderly patients with esophageal squamous cell cancer.Japanese journal of clinical oncology · 2022Review
- Prognostic Value of Pretreatment Red Blood Cell Distribution Width in Patients With Esophageal Cancer Who Underwent Esophagectomy: A Retrospective Study.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2022Article
- A study on expression level and nutritional status of IGFBP-2 after left neck anastomosis combined with placement of feeding nutritional applicators carrying ^(125)I particles in the treatment of esophageal cancer.Frontiers in oncology · 2022Article
- Prognostic Roles of Inflammation- and Nutrition-Based Indicators for Female Patients with Cancer.Journal of inflammation research · 2022Article
- Association of Modified Geriatric Nutrition Risk Index and Handgrip Strength With Survival in Cancer: A Multi-Centre Cohort Study.Frontiers in nutrition · 2022Article
- Poor nutrition and sarcopenia are related to systemic inflammatory response in patients with rectal cancer undergoing preoperative chemoradiotherapy.International journal of colorectal disease · 2022Article
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7 authors at 1 institution in 1 country.
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Abstract
backgroundThis study aimed to establish a simple and useful prognostic indicator for elderly esophageal cancer patients. We designed the modified geriatric nutrition risk index (mGNRI) using the inverse of C-reactive protein (CRP) instead of albumin and compared its prognostic value with those of the GNRI and other indices.
methodsWe included 128 patients aged > 65 years who underwent esophagectomy for esophageal cancer. We defined mGNRI as (1.489/CRP in mg/dL) + (41.7 × present/ideal body weight) and divided patients into two groups: the low-mGNRI (mGNRI < 70, n = 50) and high-mGNRI (mGNRI ≥ 70, n = 78) groups. We retrospectively examined the relationship between mGNRI and long-term prognosis.
resultsThe low-mGNRI group had more advanced cancer by stage, higher rates of recurrence, and earlier recurrence than the high-mGNRI group. Univariate analysis identified the following factors as significantly associated with poor overall survival (OS): a lower American society of anesthesiologist performance status (ASA-PS), male gender, CRP-albumin ratio ≥ 0.1, CRP ≥ 1.0, low-mGNRI, tumor depth ≥ T3, Charlson comorbidity index ≥ 2, tumor size ≥ 40 mm, and age > 75 years. A low-mGNRI, ASA-PS 3, age > 75 years, and tumor depth ≥ T3 were independent unfavorable prognostic factors for OS. A low-mGNRI was an independent poor prognostic factor for relapse-free survival. We performed model selection analysis to identify the most clinically useful indices; mGNRI was the best predictive model.
conclusionmGNRI in patients with esophageal cancer correlated with early recurrence and was a useful independent prognostic factor.
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