Evidence map›Paper›PMID 33170421›Full record

ArticleInternational ophthalmology2021

Effects of age and binarising area on choroidal vascularity index in healthy eyes: an optical coherence tomography study.

Nurullah Koçak, Mustafa Subaşı, Volkan Yeter

Abstract read
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In one paragraph

Article in International ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Impact of Optical Coherence Tomography Scan Pattern and Chorio-Scleral Interface Delineation on Choroidal Vascularity Index Measurements.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  3. Spatial distribution of Intra-retinal Hyper-reflective foci and impact on progression in eyes with intermediate Age-related macular degeneration.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Image calibration in choroidal vascularity index measurement.International journal of retina and vitreous · 2023
    Article
  8. Article
  9. Article
  10. Choroidal vascularity index in eyes with central macular atrophy secondary to age-related macular degeneration and Stargardt disease.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
  11. Macular, papillary and peripapillary perfusion densities measured with optical coherence tomography angiography in primary open angle glaucoma and pseudoexfoliation glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nurullah KoçakDepartment of Ophthalmology, Ondokuzmayıs University Hospital, Atakum, 55200, Samsun, Turkey. dr.nuric@hotmail.com.ORCID http://orcid.org/0000-0001-8811-7294
Mustafa SubaşıDepartment of Ophthalmology, Ondokuzmayıs University Hospital, Atakum, 55200, Samsun, Turkey.
Volkan YeterDepartment of Ophthalmology, Ondokuzmayıs University Hospital, Atakum, 55200, Samsun, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the changes in the choroidal vascularity index (CVI) with age and to compare the effect of the binarised area on CVI in healthy eyes using spectral-domain optical coherence tomography (SD-OCT). MATERIALS AND

methodsTwo hundred and twenty-four eyes of 224 healthy subjects were included in this prospective cross-sectional study. The eyes were divided into different age groups to analyse the possible age-related choroidal structural changes. Subfoveal choroidal thickness (SFCT), CVI, total choroidal area (TCA), stromal area (SA), luminal area (LA), and CVI within the central 1500 µm of the macula were analysed using enhanced depth imaging SD-OCT. The CVI was defined as the proportion of the LA to the TCA, and its values for the two binarised areas were compared (CVI

resultsThe mean age was 34.77 ± 20.97 (range: 5-70) years. The mean CVI

conclusionDecreased LA, TCA, and CVI were observed in healthy eyes with increasing age. CVI

Indexed as

ChoroidTomography, Optical CoherenceAdolescentAdultChildChild, PreschoolCross-Sectional StudiesHumansInfantInfant, NewbornMiddle AgedProspective StudiesRetrospective StudiesVisual AcuityYoung AdultChoroidal structureChoroidal thicknessChoroidal vascularity indexHealthy eyeOptical coherence tomography

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.