Evidence map›Paper›PMID 33170314›Full record

Observational studyInternational urogynecology journal2021

Pelvic organ prolapse after laparoscopic hysterectomy compared with vaginal hysterectomy: the POP-UP study.

Carolien K M Vermeulen, Joggem Veen, Caroline Adang, Sanne A L van Leijsen, Anne-Lotte W M Coolen, Marlies Y Bongers

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in International urogynecology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Sexual function and pelvic floor function five years after hysterectomy.Acta obstetricia et gynecologica Scandinavica · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Pelvic organ prolapse after hysterectomy: A 10-year national follow-up study.Acta obstetricia et gynecologica Scandinavica · 2023
    Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Carolien K M VermeulenDepartment of Gynecology and Obstetrics, Máxima Medical Centre, De Run 4600, 5500, MB, Veldhoven, The Netherlands. carolienvermeulen@outlook.com.ORCID http://orcid.org/0000-0003-1780-7006
Joggem VeenDepartment of Gynecology and Obstetrics, Máxima Medical Centre, De Run 4600, 5500, MB, Veldhoven, The Netherlands.
Caroline AdangDepartment of Gynecology and Obstetrics, Máxima Medical Centre, De Run 4600, 5500, MB, Veldhoven, The Netherlands.
Sanne A L van LeijsenDepartment of Gynecology and Obstetrics, Máxima Medical Centre, De Run 4600, 5500, MB, Veldhoven, The Netherlands.
Anne-Lotte W M CoolenDepartment of Gynecology and Obstetrics, Máxima Medical Centre, De Run 4600, 5500, MB, Veldhoven, The Netherlands.
Marlies Y BongersDepartment of Gynecology and Obstetrics, Máxima Medical Centre, De Run 4600, 5500, MB, Veldhoven, The Netherlands.
Radboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisThe objective was to review the long-term prevalence of pelvic organ prolapse (POP) after laparoscopic hysterectomy (LH) compared with vaginal hysterectomy (VH).

methodsAn observational cohort study was conducted amongst women who underwent an LH or a VH for benign indications during the period 1996-2004: the POP-UP study. The prevalence of POP was inventoried by a questionnaire involving the Pelvic Floor Distress Inventory (PFDI-20) and a pelvic floor examination (POP-Q). Women were divided into groups based on route and indication of hysterectomy: LH, VH-1 (for nonprolapse), and VH-2 (prolapse).

resultsFour hundred and six of the 706 eligible patients (58%) returned the questionnaire and 247 underwent POP-Q examination. Sixty-eight patients (17%) received treatment for prolapse; 8% LH, 10% VH-1, and 29% VH-2 (Chi-squared test, p < 0.001). The prevalence of vaginal vault prolapse (apical surgery or ≥ stage 2 at POP-Q) was 4.4% for LH and 5.8% for VH-1 (p = 0.707); and 23% for VH-2 (VH-2 versus others, p < 0.0001). The prevalence of prolapse ≥ stage 2 in any compartment was 62% (n = 153) in total and in 42% of the LH group, 51% of the VH-1 group, and 84% of the VH-2 group (Chi-squared test, p < 0.001). A symptomatic POP (anatomical POP ≥ stage 2 with bulging) was present in 11% of the population.

conclusionsNo difference was found in the prevalence of POP between LH and VH for nonprolapse indications. However, POP after VH for prolapse occurs more frequently than after hysterectomy for other indications.

Indexed as

LaparoscopyPelvic Organ ProlapseFemaleHumansHysterectomyHysterectomy, VaginalPelvic FloorTreatment OutcomeEpidemiologyHysterectomyLaparoscopic hysterectomyPelvic organ prolapseVaginal hysterectomy

Identifiers

PMID33170314
PMCPMC8009772
OpenAlexW3104608540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.