Evidence map›Paper›PMID 33170273›Full record

ArticleNucleic acids research2021

Gramene 2021: harnessing the power of comparative genomics and pathways for plant research.

Marcela K Tello-Ruiz, Sushma Naithani, Parul Gupta, Andrew Olson, Sharon Wei, Justin Preece, Yinping Jiao, Bo Wang, Kapeel Chougule, Priyanka Garg and 19 more

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
22.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 126 citations in OpenAlex.

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  8. GrameneOryza: a comprehensive resource for Oryza genomes, genetic variation, and functional data.Database : the journal of biological databases and curation · 2025
    Article
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 7 institutions in 3 countries.

Marcela K Tello-RuizCold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Sushma NaithaniDepartment of Botany and Plant Pathology, Oregon State University, Corvallis, OR 97331, USA.
Parul GuptaDepartment of Botany and Plant Pathology, Oregon State University, Corvallis, OR 97331, USA.
Andrew OlsonCold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Sharon WeiCold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Justin PreeceDepartment of Botany and Plant Pathology, Oregon State University, Corvallis, OR 97331, USA.
Yinping JiaoCold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Bo WangCold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Kapeel ChouguleCold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Priyanka GargDepartment of Botany and Plant Pathology, Oregon State University, Corvallis, OR 97331, USA.
Justin ElserDepartment of Botany and Plant Pathology, Oregon State University, Corvallis, OR 97331, USA.
Sunita KumariCold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Vivek KumarCold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Bruno Contreras-MoreiraEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton CB10 1SD, UK.
Guy NaamatiEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton CB10 1SD, UK.
Nancy GeorgeEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton CB10 1SD, UK.
Justin CookInformatics and Bio-computing Program, Ontario Institute of Cancer Research, Toronto M5G 1L7, Canada.
Daniel BolserEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton CB10 1SD, UK.
Peter D'EustachioDepartment of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA.
Lincoln D SteinAdaptive Oncology Program, Ontario Institute for Cancer Research, Toronto M5G 0A3, Canada.
Amit GuptaTexas Advanced Computing Center, University of Texas at Austin, Austin, TX 78758, USA.
Weijia XuTexas Advanced Computing Center, University of Texas at Austin, Austin, TX 78758, USA.
Jennifer RegalaAmerican Society of Plant Biologists, Rockville, MD 20855-2768, USA.
Irene PapatheodorouEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton CB10 1SD, UK.
Paul J KerseyEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton CB10 1SD, UK.
Paul FlicekEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton CB10 1SD, UK.
Crispin TaylorAmerican Society of Plant Biologists, Rockville, MD 20855-2768, USA.
Pankaj JaiswalDepartment of Botany and Plant Pathology, Oregon State University, Corvallis, OR 97331, USA.
Doreen WareCold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Cold Spring Harbor Laboratory · USEuropean Bioinformatics Institute · GBOregon State University · USOntario Institute for Cancer Research · CAAmerican Society of Plant Biologists · USAmerican Urological Association · USNew York University · US

Funding

Reactome - CoreU41HG003751 · NHGRI · ONTARIO INSTITUTE FOR CANCER RESEARCH · PI STEIN, LINCOLN D. · 2012 to 2021
$14.5M
Reactome: An Open Knowledgebase of Human PathwaysP41HG003751 · NHGRI · ONTARIO INSTITUTE FOR CANCER RESEARCH · PI STEIN, LINCOLN D. · 2007 to 2011
$4.5M
Biotechnology and Biological Sciences Research Council BB/P016855/1NHGRI NIH HHS P41 HG003751NHGRI NIH HHS U41 HG003751Wellcome TrustWellcome Trust 108437/Z/15/ZWellcome Trust WT101477MA
6 · The paper itself

Abstract

Gramene (http://www.gramene.org), a knowledgebase founded on comparative functional analyses of genomic and pathway data for model plants and major crops, supports agricultural researchers worldwide. The resource is committed to open access and reproducible science based on the FAIR data principles. Since the last NAR update, we made nine releases; doubled the genome portal's content; expanded curated genes, pathways and expression sets; and implemented the Domain Informational Vocabulary Extraction (DIVE) algorithm for extracting gene function information from publications. The current release, #63 (October 2020), hosts 93 reference genomes-over 3.9 million genes in 122 947 families with orthologous and paralogous classifications. Plant Reactome portrays pathway networks using a combination of manual biocuration in rice (320 reference pathways) and orthology-based projections to 106 species. The Reactome platform facilitates comparison between reference and projected pathways, gene expression analyses and overlays of gene-gene interactions. Gramene integrates ontology-based protein structure-function annotation; information on genetic, epigenetic, expression, and phenotypic diversity; and gene functional annotations extracted from plant-focused journals using DIVE. We train plant researchers in biocuration of genes and pathways; host curated maize gene structures as tracks in the maize genome browser; and integrate curated rice genes and pathways in the Plant Reactome.

Indexed as

Databases, GeneticGene Expression Regulation, PlantGenome, PlantCrops, AgriculturalDNA Transposable ElementsGene DuplicationGene OntologyGene Regulatory NetworksGenomicsInternetKnowledge BasesMetabolic Networks and PathwaysMolecular Sequence AnnotationOryzaPlant ProteinsPlantsDNA Transposable ElementsPlant Proteins

Identifiers

PMID33170273
PMCPMC7779000
OpenAlexW3104343176

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.