Evidence map›Paper›PMID 33170072›Full record

ArticleJournal of the American Heart Association2020

Association Among Noncalcified Coronary Burden, Fractional Flow Reserve, and Myocardial Injury in Psoriasis.

Wunan Zhou, Khaled M Abdelrahman, Amit K Dey, Aarthi Reddy, Domingo E Uceda, Sundus S Lateef, Youssef A Elnabawi, Paula Anzenberg, Mina Al Najafi, Justin A Rodante and 12 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Psoriasis as a Systemic Disease.Deutsches Arzteblatt international · 2024
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 3 institutions in 1 country.

Wunan ZhouNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Khaled M AbdelrahmanNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Amit K DeyNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Aarthi ReddyNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Domingo E UcedaNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Sundus S LateefNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Youssef A ElnabawiNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Paula AnzenbergNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Mina Al NajafiNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Justin A RodanteNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Andrew KeelNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Jenis OrtizNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Heather L TeagueNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Julie Erb-AlvarezNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Dolly SinghNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Aditya A JoshiNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Martin P PlayfordNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Marcus Y ChenNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
Joel M GelfandUniversity of Pennsylvania Philadelphia PA.
Alan T RemaleyNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
David A BluemkeUniversity of Wisconsin School of Medicine and Public Health Madison WI.
Nehal N MehtaNational Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD.
National Institutes of Health · USUniversity of Pennsylvania · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Myocardial infarction and premature death have been observed in patients with psoriasis. Although inflammation-driven accelerated atherosclerosis has been proposed as a mechanism, the relationship between subclinical noncalcified coronary burden (NCB), functional coronary flow impairment, and myocardial injury is unclear. Methods and Results In an ongoing longitudinal cohort study, 202 consecutive patients with psoriasis (168 at 1 year) underwent coronary computed tomography angiography to identify coronary plaque, quantify NCB, and calculate coronary fractional flow reserve by computed tomography. Serum high-sensitivity troponin-T (hs-cTn-T) was measured using a fifth-generation assay. Overall, patients were middle-aged, predominantly male, and low cardiovascular risk. A higher than median NCB associated with a positive hs-cTn-T (fully adjusted model [odds ratio (OR), 1.72; 95% CI, 1.10-2.69,

Indexed as

AdultComputed Tomography AngiographyCoronary Artery DiseaseFemaleFractional Flow Reserve, MyocardialHumansLongitudinal StudiesMaleMiddle AgedPrevalencePsoriasisTroponin TTroponin Tfractional flow reservemyocardial injurynoncalcified coronary burdenpsoriasis

Identifiers

PMID33170072
PMCPMC7763703
OpenAlexW3106382008

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.