Evidence map›Paper›PMID 33170070›Full record

ArticleJournal of the American Heart Association2020

Incorporating Latent Variables Using Nonnegative Matrix Factorization Improves Risk Stratification in Brugada Syndrome.

Gary Tse, Jiandong Zhou, Sharen Lee, Tong Liu, George Bazoukis, Panagiotis Mililis, Ian C K Wong, Cheng Chen, Yunlong Xia, Tsukasa Kamakura and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 44 citations in OpenAlex.

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  6. The value of the 12-lead electrocardiogram in the prediction of sudden cardiac death.European heart journal supplements : journal of the European Society of Cardiology · 2023
    Article
  7. Risk stratification of sudden cardiac death in asymptomatic female Brugada syndrome patients: A literature review.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 5 countries.

Gary TseTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease Department of Cardiology Tianjin Institute of Cardiology Second Hospital of Tianjin Medical University Tianjin P.R. China.
Jiandong ZhouSchool of Data Science City University of Hong Kong Hong Kong Hong Kong SAR People's Republic of China.
Sharen LeeLaboratory of Cardiovascular Physiology Chinese University Shenzhen Institute Shenzhen P.R. China.
Tong LiuTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease Department of Cardiology Tianjin Institute of Cardiology Second Hospital of Tianjin Medical University Tianjin P.R. China.
George BazoukisSecond Department of Cardiology Laboratory of Cardiac Electrophysiology Evangelismos General Hospital of Athens Athens Greece.
Panagiotis MililisSecond Department of Cardiology Laboratory of Cardiac Electrophysiology Evangelismos General Hospital of Athens Athens Greece.
Ian C K WongSchool of Pharmacy University College London London UK.
Cheng ChenDepartment of Cardiology The First Affiliated Hospital of Dalian Medical University Dalian China.
Yunlong XiaDepartment of Cardiology The First Affiliated Hospital of Dalian Medical University Dalian China.
Tsukasa KamakuraNational Cerebral and Cardiovascular Center Osaka Japan.
Takeshi AibaNational Cerebral and Cardiovascular Center Osaka Japan.
Kengo KusanoNational Cerebral and Cardiovascular Center Osaka Japan.
Qingpeng ZhangSchool of Data Science City University of Hong Kong Hong Kong Hong Kong SAR People's Republic of China.
Konstantinos P LetsasSecond Department of Cardiology Laboratory of Cardiac Electrophysiology Evangelismos General Hospital of Athens Athens Greece.
Dalian Medical University · CNEvangelismos Hospital · GRNational Cerebral and Cardiovascular Center · JPCity University of Hong Kong · HKChinese University of Hong Kong, Shenzhen · CNSecond Hospital of Tianjin Medical University · CNUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background A combination of clinical and electrocardiographic risk factors is used for risk stratification in Brugada syndrome. In this study, we tested the hypothesis that the incorporation of latent variables between variables using nonnegative matrix factorization can improve risk stratification compared with logistic regression. Methods and Results This was a retrospective cohort study of patients presented with Brugada electrocardiographic patterns between 2000 and 2016 from Hong Kong, China. The primary outcome was spontaneous ventricular tachycardia/ventricular fibrillation. The external validation cohort included patients from 3 countries. A total of 149 patients with Brugada syndrome (84% males, median age of presentation 50 [38-61] years) were included. Compared with the nonarrhythmic group (n=117, 79%), the spontaneous ventricular tachycardia/ ventricular fibrillation group (n=32, 21%) were more likely to suffer from syncope (69% versus 37%,

Indexed as

AdultAgedAlgorithmsBrugada SyndromeElectrocardiographyFemaleHong KongHumansLogistic ModelsMaleMiddle AgedPredictive Value of TestsRetrospective StudiesRisk AssessmentRisk FactorsROC CurveBrugada syndromedepolarizationECGlatent variablenonnegative matrix factorizationrepolarizationrisk stratification

Identifiers

PMID33170070
PMCPMC7763720
OpenAlexW3101385287

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.