Evidence map›Paper›PMID 33169909›Full record

ArticlePediatric dermatology2021

Consensus recommendations for the use of retinoids in ichthyosis and other disorders of cornification in children and adolescents.

Andrea L Zaenglein, Moise L Levy, Nicole S Stefanko, Latanya T Benjamin, Anna L Bruckner, Keith Choate, Brittany G Craiglow, John J DiGiovanna, Lawrence F Eichenfield, Peter Elias and 14 more

Open access · bronzeAbstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 69 citations in OpenAlex.

  1. Trial
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  11. Autosomal recessiveBMJ case reports · 2024
    Article
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  17. Review
  18. Oral Isotretinoin and Its Uses in Dermatology: A Review.Drug design, development and therapy · 2023
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 18 institutions in 1 country.

Andrea L ZaengleinDepartments of Dermatology and Pediatrics, Penn State/Hershey Medical Center and Penn State Children's Hospital, Hershey, PA, USA.ORCID https://orcid.org/0000-0002-2507-7130
Moise L LevyDepartments of Pediatrics and Medicine, Division of Dermatology, Dell Medical School, University of Texas at Austin and Dell Children's Medical Center, Austin, TX, USA.
Nicole S StefankoDivision of Dermatology, Children's Hospital of Wisconsin, Milwaukee, WI, USA.
Latanya T BenjaminDepartment of Integrated Medical Science, Florida Atlantic University, Boca Raton, FL, USA.
Anna L BrucknerDepartment of Dermatology, University of Colorado School of Medicine, Aurora, CO, USA.
Keith ChoateDepartment of Dermatology, Yale University, New Haven, CT, USA.
Brittany G CraiglowDepartment of Dermatology, Yale University, New Haven, CT, USA.ORCID https://orcid.org/0000-0001-8970-7691
John J DiGiovannaLaboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health, National Institutes of Health, Bethesda, MD, USA.
Lawrence F EichenfieldDepartments of Dermatology and Pediatrics, University of California San Diego and Rady Children's Hospital, San Diego, CA, USA.ORCID https://orcid.org/0000-0002-2760-0474
Peter EliasDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.
Philip FleckmanDepartment of Medicine, Division of Dermatology, University of Washington, Seattle, WA, USA.
Leslie P LawleyDepartment of Dermatology, Emory University School of Medicine, Atlanta, GA, USA.
Richard A LewisDepartments of Ophthalmology, Molecular and Human Genetics, Medicine and Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Anne W LuckyDepartment of Pediatrics, Division of Dermatology, Cincinnati Children's Hospital, Cincinnati, OH, USA.ORCID https://orcid.org/0000-0002-6115-7584
Erin F MathesDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.
Leonard M MilstoneDepartment of Dermatology, Yale University, New Haven, CT, USA.
Amy S PallerDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Sonali S PatelDepartment of Pediatrics, Section of Cardiology, University of Colorado School of Medicine, Aurora, CO, USA.
Dawn H SiegelDepartment of Dermatology, Medical College of Wisconsin, Milwaukee, WI, USA.
Joyce TengDepartment of Dermatology, Stanford University, Stanford, CA, USA.
Sherry A TanumihardjoDepartment of Nutritional Sciences, University of Wisconsin, Madison, WI, USA.
Lauren ThaxtonDepartment of Women's Health, University of Texas at Austin Dell Medical School, Austin, TX, USA.
Mary L WilliamsDepartments of Dermatology and Pediatrics, University of California, San Francisco, San Francisco, CA, USA.
PeDRA Use of Retinoids in Ichthyosis Work Group
University of California, San Francisco · USYale University · USUniversity of Colorado Denver · USBaylor College of Medicine · USChildren's Hospital of Wisconsin · USCincinnati Children's Hospital Medical Center · USDell Children's Medical Center of Central Texas · USEmory University · USFlorida Atlantic University · USMedical College of Wisconsin · USNational Institutes of Health · USNorthwestern University · USPenn State Milton S. Hershey Medical Center · USStanford University · USThe University of Texas at Austin · USUniversity of California San Diego · USUniversity of Washington · USUniversity of Wisconsin–Madison · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Foundation for Ichthyosis and Related Skin TypesNCATS NIH HHS UL1 TR001863Sun Pharmaceuticals
6 · The paper itself

Abstract

Topical and systemic retinoids have long been used in the treatment of ichthyoses and other disorders of cornification. Due to the need for long-term use of retinoids for these disorders, often beginning in childhood, numerous clinical concerns must be considered. Systemic retinoids have known side effects involving bone and eye. Additionally, potential psychiatric and cardiovascular effects need to be considered. Contraceptive concerns, as well as the additive cardiovascular and bone effects of systemic retinoid use with hormonal contraception must also be deliberated for patients of childbearing potential. The Pediatric Dermatology Research Alliance (PeDRA) Use of Retinoids in Ichthyosis Work Group was formed to address these issues and to establish best practices regarding the use of retinoids in ichthyoses based on available evidence and expert opinion.

Indexed as

IchthyosisIchthyosis, LamellarAdolescentChildHumansRetinoidsRetinoidsadverse drug effectsbone healthcontraceptiondepressiondisorder of cornificationdrug monitoringectropionhyperlipidemiaichthyosisiPLEDGEquality of liferetinoidsafety monitoringsystemic therapytopical therapy

Identifiers

PMID33169909
PMCPMC7984068
OpenAlexW3098447102

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.