ArticleJournal of Korean medical science2020
Serum Calprotectin Is a Potential Marker in Patients with Asthma.
Article in Journal of Korean medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Serum calprotectin as a biomarker for postoperative complications in colorectal surgery: a pilot study defining normal postoperative dynamics.BMC surgery · 2025Article
- A review on clinical implications of S100 proteins in lung diseases.Frontiers in medicine · 2025Review
- Causal Association Between 12 Micronutrients and Common Chronic Respiratory Diseases: A Bidirectional Two-Sample Mendelian Randomization Study.Genetics research · 2025Article
- Calprotectin is regulated by IL-17A and induces steroid hyporesponsiveness in asthma.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024Article
- Update on Inflammatory Biomarkers for Defining Asthma Phenotype.Allergy, asthma & immunology research · 2024Review
- Serum Calprotectin in the Evaluation of Gastrointestinal Diseases: An Ace up Your Sleeve?Medicina (Kaunas, Lithuania) · 2024Review
- Abnormal S100A8 expression associates with postoperative recurrence in chronic rhinosinusitis with nasal polyps.Heliyon · 2024Article
- Article
- S100A alarmins and thymic stromal lymphopoietin (TSLP) regulation in severe asthma following bronchial thermoplasty.Respiratory research · 2023Article
- Neutrophil Extracellular Traps in Airway Diseases: Pathological Roles and Therapeutic Implications.International journal of molecular sciences · 2023Review
- Olfactomedin 4 as a circulating biomarker for asthma.Annals of translational medicine · 2022Article
- Neutrophil extracellular traps in chronic lung disease: implications for pathogenesis and therapy.European respiratory review : an official journal of the European Respiratory Society · 2022Review
- Expression profiling of ileal mucosa in asthma reveals upregulation of innate immunity and genes characteristic of Paneth and goblet cells.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2021Article
- Calprotectin: An Ignored Biomarker of Neutrophilia in Pediatric Respiratory Diseases.Children (Basel, Switzerland) · 2021Review
- Assessment of Inflammatory Markers in Children with Cow's Milk Allergy Treated with a Milk-Free Diet.Nutrients · 2021Article
- Roxithromycin attenuates inflammation via modulation of RAGE-influenced calprotectin expression in a neutrophilic asthma model.Annals of translational medicine · 2021Article
- Calprotectin in Lung Diseases.International journal of molecular sciences · 2021Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundCalprotectin is the major cytosolic protein in neutrophil granulocytes. Although asthma is known to cause eosinophilic inflammation, some patients with asthma have non-eosinophilic inflammation, which is characterized by local neutrophilic inflammation. The aim of this study was to assess calprotectin expression levels in a mouse model of asthma, and to observe the relationship of serum calprotectin level and clinical variables in patients with asthma.
methodsMice were sensitized and challenged with 10 μg and 20 μg of
resultsCalprotectin, S100A8, and S100A9 expression was elevated in the mouse lungs, calprotectin levels were higher in the serum of patients with asthma (n = 33) compared with those of healthy individuals (n = 28). Calprotectin levels correlated with forced expiratory volume in one second/forced vital capacity (
conclusionOur data suggest that calprotectin could potentially be used as a biomarker for asthma.
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Registered trials
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