Evidence map›Paper›PMID 33169339›Full record

SynthesisHeart failure reviews2021

Impact of atrial fibrillation on the outcomes of transcatheter mitral valve repair using MitraClip: a systematic review and meta-analysis.

Siddharth Shah, Vijay Raj, Mahmoud Abdelghany, Carlos Mena-Hurtado, Sana Riaz, Siddharth Patel, Howard Wiener, Debanik Chaudhuri

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Heart failure reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Siddharth ShahDepartment of Medicine, Division of Cardiology, State University of New York Upstate Medical University, 750 E Adams Street, Syracuse, NY, 13210, USA. drsshah22@gmail.com.ORCID 0000-0001-8702-3026
Vijay RajDepartment of Medicine, Division of Cardiology, State University of New York Upstate Medical University, 750 E Adams Street, Syracuse, NY, 13210, USA.
Mahmoud AbdelghanyPioneer Valley Cardiology, University of Massachusetts/ Baystate Medical Center, Mercy Medical Center, Springfield, MA, USA.
Carlos Mena-HurtadoDepartment of Medicine, Division of Cardiology, Yale University School of Medicine, New Haven, CT, USA.
Sana RiazDepartment of Medicine, State University of New York Upstate Medical University, Syracuse, NY, USA.
Siddharth PatelDepartment of Pulmonary, Allergy and Critical care, University of Alabama at Birmingham, Birmingham, AL, USA.
Howard WienerDepartment of Epidemiology, University of Alabama at Birmingham School of Public Health, Birmingham, AL, USA.
Debanik ChaudhuriDepartment of Medicine, Division of Cardiology, State University of New York Upstate Medical University, 750 E Adams Street, Syracuse, NY, 13210, USA.
SUNY Upstate Medical University · USUniversity of Alabama at Birmingham · USBaystate Medical Center · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) is a common arrhythmia in patients with mitral regurgitation (MR) undergoing transcatheter mitral valve repair (TMVR). In this systematic review, we aimed to investigate the outcomes of TMVR using MitraClip in AF patients. We performed a systematic search using PubMed, SCOPUS, EMBASE, and Google Scholar, from inception to May 10, 2020, for studies that reported outcomes following MitraClip, in patients with AF versus without AF. Seven studies with a total of 7678 patients met the inclusion criteria. The risk of 1-year all-cause mortality following TMVR was higher in AF patients (RR 1.40, 95% CI 1.27-1.54, p ≤ 0.001). Similarly, the risk of heart failure hospitalization was higher in patients with AF (RR 1.17, 95% CI 1.06-1.30, p = 0.002) and the risk of bleeding was elevated in AF patients (RR 1.29, 95% CI 1.15-1.45, p ≤ 0.001). The risk of procedural failure, in-hospital mortality, cardiovascular mortality, and stroke was not significantly different between the two groups. The higher risk of all-cause mortality, HF hospitalization, and risk of bleeding in AF patients undergoing MitraClip warrants attention.

Indexed as

Atrial FibrillationHeart Valve Prosthesis ImplantationMitral Valve InsufficiencyCardiac CatheterizationHumansMitral ValveTreatment OutcomeAtrial fibrillationMitraClipMitral regurgitationTranscatheter mitral valve repair

Identifiers

PMID33169339
OpenAlexW3098731201

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.