ReviewIntensive care medicine2020
How to ventilate obstructive and asthmatic patients.
Review in Intensive care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 69 citations in OpenAlex.
- End-inspiratory pause enhances ventilation efficiency without increasing autoPEEP in patients with COPD during controlled ventilation.Critical care (London, England) · 2026Trial
- Effects of preconditioning with one-lung ventilation on perioperative oxygenation and oxidative stress in thoracoscopic surgery: a prospective single-center randomized controlled clinical trial.BMC anesthesiology · 2026Trial
- Asthma exacerbation requiring ventilatory support in adults: a 10-year retrospective multicentre cohort study - the ESAVA study.BMJ open respiratory research · 2026Article
- Short-Term Physiological Effects of Moderate PEEP Levels in Invasively Ventilated Patients Without Acute or Chronic Lung Disease.Medical sciences (Basel, Switzerland) · 2026Article
- Dead space in critical care: a practical approach with clinical scenarios.Journal of anesthesia, analgesia and critical care · 2026Review
- Effect modification by chronic obstructive pulmonary disease, anion gap, and serum creatinine on the association between invasive mechanical ventilation and 28-day mortality in intensive care unit sepsis patients: a retrospective cohort study.Frontiers in medicine · 2026Article
- Chronic phase ventilation strategy in established severe bronchopulmonary dysplasia: A critical evaluation of the evidence.SAGE open medicine · 2026Review
- Chain management reduces inflammation (IL-1b, IL-6, IL-8, TNF-a, PCT) and improves vascular (NO, DD, VWF, and ET-1)/immune function in acute respiratory failure: A retrospective cohort study.Journal of medical biochemistry · 2025Article
- Troubleshooting Severe Airflow Obstruction With a Pressure-Limited Transport Ventilator: Lessons From Two Cases.Critical care explorations · 2025Article
- Magnesium sulfate in oxidative stress-associated pathologies: clinical, cellular, and molecular perspectives.Biophysical reviews · 2025Review
- Management of Asthma and COPD Exacerbations in Adults in the ICU.CHEST critical care · 2025Article
- An Updated Review on the Use of Noninvasive Respiratory Supports in the Management of Severe Asthma Exacerbations.Medicina (Kaunas, Lithuania) · 2025Review
- Association Between Mechanical Power and 28-Day All-Cause Mortality in Chronic Obstructive Pulmonary Disease Patients Undergoing Invasive Ventilation: Analysis of the MIMIC-IV Database.International journal of chronic obstructive pulmonary disease · 2025Observational
- Bedside Assessment of the Respiratory System During Invasive Mechanical Ventilation.Journal of clinical medicine · 2024Review
- Severe respiratory syncytial virus disease.Journal of intensive medicine · 2024Review
- Status Asthmaticus in the Pediatric ICU: A Comprehensive Review of Management and Challenges.Pediatric reports · 2024Review
- Early and late effects of volatile sedation with sevoflurane on respiratory mechanics of critically ill COPD patients.Annals of intensive care · 2024Article
- Institutional Variability in Respiratory Support Use for Pediatric Critical Asthma: A Multicenter Retrospective Study.Annals of the American Thoracic Society · 2024Article
- Evaluation of antibody drug delivery efficiency via nebulizer in various airway models and breathing patterns.BMC pharmacology & toxicology · 2023Article
- Non-ventilator-associated ICU-acquired pneumonia (NV-ICU-AP) in patients with acute exacerbation of COPD: From the French OUTCOMEREA cohort.Critical care (London, England) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 11 institutions in 9 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exacerbations are part of the natural history of chronic obstructive pulmonary disease and asthma. Severe exacerbations can cause acute respiratory failure, which may ultimately require mechanical ventilation. This review summarizes practical ventilator strategies for the management of patients with obstructive airway disease. Such strategies include non-invasive mechanical ventilation to prevent intubation, invasive mechanical ventilation, from the time of intubation to weaning, and strategies intended to prevent post-extubation acute respiratory failure. The role of tracheostomy, the long-term prognosis, and potential future adjunctive strategies are also discussed. Finally, the physiological background that underlies these strategies is detailed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.