Evidence map›Paper›PMID 33169181›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2021

Serum prolidase, malondialdehyde and catalase levels for the evaluation of oxidative stress in patients with peripheral vertigo.

Isa Ozbay, Muhammet Fatih Topuz, Fatih Oghan, Havva Kocak, Cuneyt Kucur

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Isa OzbayDepartment of Otolaryngology, Atasehir Avicenna Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-6894-0451
Muhammet Fatih TopuzDepartment of Otolaryngology, Kutahya Saglık Bilimleri University, Kutahya, Turkey.ORCID http://orcid.org/0000-0002-7996-662X
Fatih OghanDepartment of Otolaryngology, Kutahya Saglık Bilimleri University, Kutahya, Turkey. fatih.oghan@ksbu.edu.tr.ORCID http://orcid.org/0000-0002-2021-1839
Havva KocakDepartment of Biochemistry, Kutahya Saglık Bilimleri University, Kutahya, Turkey.ORCID http://orcid.org/0000-0002-7147-0179
Cuneyt KucurDepartment of Otolaryngology, Bezmi Alem Vakıf University, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-1494-0653
Dumlupinar University · TRBezmiâlem Vakıf Üniversitesi · TRIstanbul Memorial Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to evaluate oxidative stress in patients with peripheral vertigo by measuring serum prolidase, malondialdehyde (MDA) and catalase levels.

methodsA total of 30 patients (age: 60 <) with peripheral vertigo and 30 healthy subjects were recruited. Blood samples were collected from both groups and serum prolidase levels were measured using enzyme-linked immunosorbent assay (ELISA). MDA and catalase levels were measured by the spectrophotometric method.

resultsThe most common cause of vertigo was BPPV (53.3%), followed by Ménière's disease (16.6%), vestibular neuritis (13.3%), lateral semicircular canal fistula (3.3%), and idiopathic vertigo (13.3%). Mean serum prolidase activity and MDA levels were significantly higher in the vertigo patients than in the control subjects (P < 0.05); however, there was no statistically significant difference in mean serum catalase levels between the groups (P > 0.05).

conclusionWe concluded that serum prolidase and MDA levels may be used as markers of oxidative stress in patients with peripheral vertigo.

Indexed as

Oxidative StressVertigoCatalaseDipeptidasesHumansMalondialdehydeMiddle AgedCatalaseDipeptidasesMalondialdehydeproline dipeptidaseCatalaseMalondialdehydeOxidative stressPeripheral vertigoProlidase

Identifiers

PMID33169181
OpenAlexW3104952685

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.