Evidence map›Paper›PMID 33168895›Full record

ArticleScientific reports2020

A fast and fully-automated deep-learning approach for accurate hemorrhage segmentation and volume quantification in non-contrast whole-head CT.

Ali Arab, Betty Chinda, George Medvedev, William Siu, Hui Guo, Tao Gu, Sylvain Moreno, Ghassan Hamarneh, Martin Ester, Xiaowei Song

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  14. A revolutionary acute subdural hematoma detection based on two-tiered artificial intelligence model.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ali ArabSchool of Computing Science, Simon Fraser University, Burnaby, BC, Canada.
Betty ChindaDepartment of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, BC, Canada.
George MedvedevDivision of Neurology, Royal Columbian Hospital, New Westminster, BC, Canada.
William SiuDivision of Radiology, Royal Columbian Hospital, New Westminster, BC, Canada.
Hui GuoHealth Sciences and Innovation, Surrey Memorial Hospital, Fraser Health Authority, Surrey, BC, Canada.
Tao GuHealth Sciences and Innovation, Surrey Memorial Hospital, Fraser Health Authority, Surrey, BC, Canada.
Sylvain MorenoSchool of Interactive Arts and Technology, Simon Fraser University, Surrey, BC, Canada.
Ghassan HamarnehSchool of Computing Science, Simon Fraser University, Burnaby, BC, Canada.
Martin EsterSchool of Computing Science, Simon Fraser University, Burnaby, BC, Canada. ester@sfu.ca.
Xiaowei SongDepartment of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, BC, Canada. Xiaowei.Song@fraserhealth.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This project aimed to develop and evaluate a fast and fully-automated deep-learning method applying convolutional neural networks with deep supervision (CNN-DS) for accurate hematoma segmentation and volume quantification in computed tomography (CT) scans. Non-contrast whole-head CT scans of 55 patients with hemorrhagic stroke were used. Individual scans were standardized to 64 axial slices of 128 × 128 voxels. Each voxel was annotated independently by experienced raters, generating a binary label of hematoma versus normal brain tissue based on majority voting. The dataset was split randomly into training (n = 45) and testing (n = 10) subsets. A CNN-DS model was built applying the training data and examined using the testing data. Performance of the CNN-DS solution was compared with three previously established methods. The CNN-DS achieved a Dice coefficient score of 0.84 ± 0.06 and recall of 0.83 ± 0.07, higher than patch-wise U-Net (< 0.76). CNN-DS average running time of 0.74 ± 0.07 s was faster than PItcHPERFeCT (> 1412 s) and slice-based U-Net (> 12 s). Comparable interrater agreement rates were observed between "method-human" vs. "human-human" (Cohen's kappa coefficients > 0.82). The fully automated CNN-DS approach demonstrated expert-level accuracy in fast segmentation and quantification of hematoma, substantially improving over previous methods. Further research is warranted to test the CNN-DS solution as a software tool in clinical settings for effective stroke management.

Indexed as

Deep LearningTomography, X-Ray ComputedAgedFemaleHeadHumansIntracranial HemorrhagesMaleMiddle Aged

Identifiers

PMID33168895
PMCPMC7652921

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.