Evidence map›Paper›PMID 33168859›Full record

ArticleScientific reports2020

Estimation of optimal number of gates in dual gated

R Klén, J Teuho, T Noponen, K Thielemans, E Hoppela, E Lehtonen, H T Sipila, M Teräs, J Knuuti

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. From incidental positron emission uptake toFrontiers in cardiovascular medicine · 2026
    Review
  2. Effect of respiratory motion correction and CT-based attenuation correction on dual-gated cardiac PET image quality and quantification.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

R KlénTurku PET Centre, Turku University Hospital, University of Turku, Turku, Finland. riku.klen@utu.fi.
J TeuhoTurku PET Centre, Turku University Hospital, University of Turku, Turku, Finland.
T NoponenDivision of Medical Imaging, Department of Medical Physics, Turku University Hospital, Turku, Finland.
K ThielemansUniversity College London, London, UK.
E HoppelaTurku PET Centre, Turku University Hospital, University of Turku, Turku, Finland.
E LehtonenDepartment of Future Technologies, University of Turku, Turku, Finland.
H T SipilaTurku PET Centre, Turku University Hospital, University of Turku, Turku, Finland.
M TeräsDivision of Medical Imaging, Department of Medical Physics, Turku University Hospital, Turku, Finland.
J KnuutiTurku PET Centre, Turku University Hospital, University of Turku, Turku, Finland.
Turku University Hospital · FIUniversity of Turku · FIHammersmith Hospital · GBTurku PET Centre · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gating of positron emission tomography images has been shown to reduce the motion effects, especially when imaging small targets, such as coronary plaques. However, the selection of optimal number of gates for gating remains a challenge. Selecting too high number of gates results in a loss of signal-to-noise ratio, while too low number of gates does remove only part of the motion. Here, we introduce a respiratory-cardiac motion model to determine the optimal number of respiratory and cardiac gates. We evaluate the model using a realistic heart phantom and data from 12 cardiac patients (47-77 years, 64.5 on average). To demonstrate the benefits of our model, we compared it with an existing respiratory model. Based on our study, the optimal number of gates was determined to be five respiratory and four cardiac gates in the phantom and patient studies. In the phantom study, the diameter of the most active hot spot was reduced by 24% in the dual gated images compared to non-gated images. In the patient study, the thickness of myocardium wall was reduced on average by 21%. In conclusion, the motion model can be used for estimating the optimal number of respiratory and cardiac gates for dual gating.

Indexed as

Positron Emission Tomography Computed TomographyAgedAlgorithmsCardiovascular DiseasesFemaleFluorodeoxyglucose F18HeartHumansImage Processing, Computer-AssistedMaleMiddle AgedMotionPhantoms, ImagingRespirationSignal-To-Noise RatioFluorodeoxyglucose F18

Identifiers

PMID33168859
PMCPMC7653943
OpenAlexW3103124765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.