Evidence map›Paper›PMID 33168737›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Stac protein regulates release of neuropeptides.

I-Uen Hsu, Jeremy W Linsley, Xiaoli Zhang, Jade E Varineau, Drew A Berkhoudt, Lilly E Reid, Miranda C Lum, Allison M Orzel, Ari Leflein, Haoxing Xu and 4 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. A molecular atlas of adultbioRxiv : the preprint server for biology · 2023
    Article
  7. eLife · 2022
    Article
  8. Activity-dependent modulation of neuronal KThe Journal of biological chemistry · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

I-Uen HsuDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0002-4089-6601
Jeremy W LinsleyDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0001-6464-8728
Xiaoli ZhangDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0002-0507-6317
Jade E VarineauDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.
Drew A BerkhoudtDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261.
Lilly E ReidDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0003-0516-391X
Miranda C LumDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.
Allison M OrzelDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.
Ari LefleinDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.
Haoxing XuDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0003-3561-4654
Catherine A CollinsDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0002-1608-6692
Richard I HumeDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0001-9807-112X
Edwin S LevitanDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261.ORCID 0000-0003-3319-1344
John Y KuwadaDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109; kuwada@umich.edu.
University of Michigan · USUniversity of Pittsburgh · US

Funding

Dense-Core Vesicle Circulation, Capture and Synaptic Neuropeptide ReleaseR01NS032385 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI EDWIN S LEVITAN · 1995 to 2026
$13.0M
CELLULAR AND MOLECULAR BIOLOGY AT MICHIGANT32GM007315 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PUTHENVEEDU, MANOJKUMAR A · 1985 to 2021
$12.8M
Regenerative and Degenerative Responses to Axonal InjuryR01NS069844 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CADIGAN, KENNETH M, COLLINS, CATHERINE A · 2010 to 2024
$5.0M
Analysis of a Novel Regulator of Excitation-Contraction Coupling in Skeletal MuscR01AR063056 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KUWADA, JOHN Y · 2013 to 2017
$1.8M
NIAMS NIH HHS R01 AR063056NIGMS NIH HHS T32 GM007315NINDS NIH HHS R01 NS032385NINDS NIH HHS R01 NS069844
6 · The paper itself

Abstract

Neuropeptides are important for regulating numerous neural functions and behaviors. Release of neuropeptides requires long-lasting, high levels of cytosolic Ca

Indexed as

AnimalsAnimals, Genetically ModifiedBehavior, AnimalBehavior Observation TechniquesCalcium ChannelsDrosophila melanogasterDrosophila ProteinsFemaleIntracellular Signaling Peptides and ProteinsIntravital MicroscopyLarvaMaleModels, AnimalMotor NeuronsMuscle, SkeletalNeuromuscular JunctionCa-alpha1D protein, DrosophilaCalcium ChannelsDrosophila ProteinsIntracellular Signaling Peptides and ProteinsNeuropeptidesStacl protein, DrosophilaDrosophila melanogasterL-type voltage-gated calcium channelneuropeptidestac

Identifiers

PMID33168737
PMCPMC7703553
OpenAlexW3104261583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.