Evidence map›Paper›PMID 33168716›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis.

Heddy Soufari, Florent Waltz, Camila Parrot, Stéphanie Durrieu-Gaillard, Anthony Bochler, Lauriane Kuhn, Marie Sissler, Yaser Hashem

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Mechanistic insights intobioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
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  11. Insights into Peptidyl-ProlylPathogens (Basel, Switzerland) · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Mitoribosome Biogenesis.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Heddy SoufariInstitut Européen de Chimie et Biologie, U1212 INSERM, UMR5320 CNRS, Université de Bordeaux, F-33600 Pessac, France.
Florent WaltzInstitut Européen de Chimie et Biologie, U1212 INSERM, UMR5320 CNRS, Université de Bordeaux, F-33600 Pessac, France.ORCID 0000-0002-2251-3363
Camila ParrotInstitut Européen de Chimie et Biologie, U1212 INSERM, UMR5320 CNRS, Université de Bordeaux, F-33600 Pessac, France.
Stéphanie Durrieu-GaillardInstitut Européen de Chimie et Biologie, U1212 INSERM, UMR5320 CNRS, Université de Bordeaux, F-33600 Pessac, France.
Anthony BochlerInstitut Européen de Chimie et Biologie, U1212 INSERM, UMR5320 CNRS, Université de Bordeaux, F-33600 Pessac, France.
Lauriane KuhnPlateforme Protéomique Strasbourg Esplanade FRC1589 du CNRS, Université de Strasbourg, 67000 Strasbourg, France.ORCID 0000-0002-2637-1024
Marie SisslerInstitut Européen de Chimie et Biologie, U1212 INSERM, UMR5320 CNRS, Université de Bordeaux, F-33600 Pessac, France; m.sissler@iecb.u-bordeaux.fr yaser.hashem@inserm.fr.ORCID 0000-0001-8594-5238
Yaser HashemInstitut Européen de Chimie et Biologie, U1212 INSERM, UMR5320 CNRS, Université de Bordeaux, F-33600 Pessac, France; m.sissler@iecb.u-bordeaux.fr yaser.hashem@inserm.fr.ORCID 0000-0003-4264-5918
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kinetoplastids are unicellular eukaryotic parasites responsible for such human pathologies as Chagas disease, sleeping sickness, and leishmaniasis. They have a single large mitochondrion, essential for the parasite survival. In kinetoplastid mitochondria, most of the molecular machineries and gene expression processes have significantly diverged and specialized, with an extreme example being their mitochondrial ribosomes. These large complexes are in charge of translating the few essential mRNAs encoded by mitochondrial genomes. Structural studies performed in

Indexed as

Antiprotozoal AgentsChagas DiseaseCryoelectron MicroscopyHumansLeishmaniaLeishmaniasisMitochondrial RibosomesModels, MolecularRibosomal ProteinsRibosome Subunits, Large, EukaryoticRNA Processing, Post-TranscriptionalRNA, RibosomalTrypanosoma cruziAntiprotozoal AgentsRibosomal ProteinsRNA, Ribosomalcryo-electron microscopykinetoplastidsmitochondrial ribosomemRNA translationribosome biogenesis

Identifiers

PMID33168716
PMCPMC7703582
OpenAlexW3102678349

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.