Evidence map›Paper›PMID 33168606›Full record

ArticleAntimicrobial agents and chemotherapy2021

Pharmacodynamics of Posaconazole in Experimental Invasive Pulmonary Aspergillosis: Utility of Serum Galactomannan as a Dynamic Endpoint of Antifungal Efficacy.

Silke Gastine, William Hope, Georg Hempel, Ruta Petraitiene, Vidmantas Petraitis, Diana Mickiene, John Bacher, Thomas J Walsh, Andreas H Groll

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Assessment of Antifungal Pharmacodynamics.Journal of fungi (Basel, Switzerland) · 2023
    Article
  6. Article
  7. A Review of Population Pharmacokinetic Models of Posaconazole.Drug design, development and therapy · 2022
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Silke GastineInstitute of Pharmaceutical and Medical Chemistry, Department of Clinical Pharmacy, Westfälische Wilhelms-Universität Münster, Münster, Germany.ORCID 0000-0002-1069-6123
William HopeCentre of Excellence in Infectious Diseases Research, Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0001-6187-878X
Georg HempelInstitute of Pharmaceutical and Medical Chemistry, Department of Clinical Pharmacy, Westfälische Wilhelms-Universität Münster, Münster, Germany.
Ruta PetraitieneTransplantation-Oncology Infectious Diseases Program, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine of Cornell University, New York, New York, USA.
Vidmantas PetraitisTransplantation-Oncology Infectious Diseases Program, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine of Cornell University, New York, New York, USA.
Diana MickieneLaboratory Animal Sciences Program, SAIC-Frederick, Inc., Frederick, Maryland, USA.
John BacherSurgery Service, Veterinary Resources Program, Office of Research Services, National Institutes of Health, Bethesda, Maryland, USA.
Thomas J WalshDepartment of Pediatrics, Weill Cornell Medicine of Cornell University, New York, New York, USA.
Andreas H GrollInfectious Disease Research Program, Center for Bone Marrow Transplantation and Department of Pediatric Hematology/Oncology, University Children's Hospital Münster, Münster, Germany andreas.groll@ukmuenster.de.
Cornell University · USUniversity of Münster · DENational Institutes of Health · USScience Applications International Corporation (United States) · USUniversity Hospital Münster · DEUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Invasive Pulmonary AspergillosisAnimalsAntifungal AgentsDisease Models, AnimalGalactoseHumansMannansMicrobial Sensitivity TestsRabbitsTriazolesAntifungal AgentsgalactomannanGalactoseMannansposaconazoleTriazolesaspergillosisgalactomannanmodellingpharmacodynamicspharmacokineticsPK/PD modellingpopulation pharmacokineticsposaconazole

Identifiers

PMID33168606
PMCPMC7848991
OpenAlexW3096210596

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.