Evidence map›Paper›PMID 33168011›Full record

ArticleJournal of nanobiotechnology2020

Self-assembled bovine serum albumin nanoparticles as pesticide delivery vectors for controlling trunk-boring pests.

Chenyu Su, Shanshan Liu, Shenghan Cao, Shuyan Yin, Chenggang Zhou, Shangkun Gao, Chunyan Jia, Yingchao Ji, Yanxue Liu

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
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  4. Review
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  6. Article
  7. Spectroscopic Analysis of the Binding of Paraquat and Diquat Herbicides to Biosubstrates.International journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chenyu SuCollege of Plant Protection, Shandong Agricultural University, Tai'an, 271018, Shandong, People's Republic of China.
Shanshan LiuCollege of Plant Protection, Shandong Agricultural University, Tai'an, 271018, Shandong, People's Republic of China.
Shenghan CaoCollege of Plant Protection, Shandong Agricultural University, Tai'an, 271018, Shandong, People's Republic of China.
Shuyan YinCollege of Plant Protection, Shandong Agricultural University, Tai'an, 271018, Shandong, People's Republic of China.
Chenggang ZhouCollege of Plant Protection, Shandong Agricultural University, Tai'an, 271018, Shandong, People's Republic of China.
Shangkun GaoCollege of Plant Protection, Shandong Agricultural University, Tai'an, 271018, Shandong, People's Republic of China.
Chunyan JiaTaishan Scenery and Scenic Spot Area Management Committee, Tai'an, 271000, Shandong, People's Republic of China.
Yingchao JiCollege of Plant Protection, Shandong Agricultural University, Tai'an, 271018, Shandong, People's Republic of China. jiyc2018@sdau.edu.cn.
Yanxue LiuCollege of Animal and Veterinary Medicine, Shandong Agricultural University, Tai'an, 271018, Shandong, People's Republic of China. liuyouyou2018@163.com.
Shandong Agricultural University · CNTaishan University · CN

Funding

Shandong Agricultural Science and Technology Innovation (Forestry Science and Technology Innovation) Project 2019LY003
6 · The paper itself

Abstract

backgroundTrunk-boring pests (TBPs) are an important type of forest pest, TBPs not only feed on the branches and trunks of trees, but also spread quarantine diseases in forests. However, because the larvae of TBPs live inside the trunk and are well concealed, prevention and control are difficult. The lack of effective control methods leads to the death of many trees in forests. In this study, a novel nanopesticide featuring high bioactivity and slow-release properties was developed to control TBPs. Thiacloprid (THI), which is commonly used to control Coleoptera species, was used as a model pesticide.

resultsThe oleophobic properties of bovine serum albumin (BSA) were exploited to encapsulate the hydrophobic pesticide THI by self-assembly, and the size of the obtained nanoparticles, THI@BSA·NPs, was approximately 23 nm. The loading efficiency reached 70.4%, and THI@BSA·NPs could be released continuously for over 15 days, with the cumulative release reaching 93.5%. The fluorescein isothiocyanate (FITC)-labeled nanoparticles were evenly distributed in the digestive tract and body surface of a typical TBPs, M. alternatus, and the stomach and contact toxicities increased by 33.7% and 25.9%, respectively, compared with those of free THI. Furthermore, the results showed that the transport efficiency of THI@BSA·NPs was highest at a concentration of 50 μg/mL, and the THI@BSA·NPs content in the trunk, from to lower to higher layers, was 8.8, 8.2, 7.6, and 5.8 μg/g. At the same time, THI@BSA·NPs also exhibited high transport efficiency in dead trees.

conclusionThe transport efficiency and toxicity of the active ingredients are the key factors for the control of TBPs. This work provided idea for the application of biological delivery system encapsulated hydrophobic pesticides. The novel self-assembled THI@BSA·NPs have promising potential for sustainable control of TBPs.

Indexed as

AnimalsCell Line, TumorDrug CarriersLarvaNanoparticlesNeonicotinoidsParticle SizePesticidesSerum Albumin, BovineStomachThiazinesTreesDrug CarriersNeonicotinoidsPesticidesSerum Albumin, BovinethiaclopridThiazinesBovine serum albuminNano-pesticideSelf-assemblyThiaclopridTrunk-boring pests

Identifiers

PMID33168011
PMCPMC7653776
OpenAlexW3098002395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.