SynthesisRespiratory research2020
The association between serum vitamin D and obstructive sleep apnea: an updated meta-analysis.
Synthesis in Respiratory research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Serum 25(OH)D levels and obstructive sleep apnea syndrome severity in patients without comorbidities: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2024Pooled it
- Obstructive sleep apnea and vitamin D: an updated systematic review and meta-analysis.Hormones (Athens, Greece) · 2023Pooled it
- An umbrella review of systematic reviews and meta-analyses of observational investigations of obstructive sleep apnea and health outcomes.Sleep & breathing = Schlaf & Atmung · 2022Pooled it
- Vitamin D Deficiency Is Associated with a Higher 5-Year Risk of Obstructive Sleep Apnea and CPAP Use in Older Adults: An Anchor-Based Network Meta-Analysis.Medicina (Kaunas, Lithuania) · 2026Article
- Comparative Diagnostic Performance of Serum α-Klotho and FGF-23 in Predicting Obstructive Sleep Apnea Severity: A Novel Biomarker Approach.Journal of clinical medicine · 2026Article
- Vitamin D and Mean Platelet Volume as Biomarkers in Pediatric Obstructive Sleep Apnea: Associations with Disease Severity and Sleep Parameters.Journal of clinical medicine · 2026Article
- Predictors of vitamin D deficiency and quality of life in obese patients with obstructive sleep apnea.Scientific reports · 2026Article
- Vitamin D deficiency and risk of heart failure in patients with obstructive sleep apnea: a cohort analysis.Frontiers in nutrition · 2026Article
- Association between vertebral fracture risk and bone mineral density in patients with acromegaly.Pituitary · 2025Article
- Association between serum 25-hydroxyvitamin D and snoring in adults in Northern sudan: a matched case-control study.Scientific reports · 2025Article
- Vitamin D Deficiency and Its Role in Pathologies of Oxidative Stress: A Literature Review.Cureus · 2025Review
- Vitamin D deficiency and subsequent risk of obstructive sleep apnea: a multi-institutional retrospective study.Frontiers in nutrition · 2025Article
- A Prospective Observational Study Investigating the Relationship Between Vitamin D Deficiency and STOP-Bang Parameters in Elderly Populations.Nature and science of sleep · 2025Article
- The role of interaction between vitamin D and VDR FokI gene polymorphism (rs2228570) in sleep quality of adults.Scientific reports · 2024Article
- Obstructive sleep apnea and vitamin D level: Has the dust settled?The clinical respiratory journal · 2024Review
- Associations between Vitamin D Status and Polysomnographic Parameters in Adults with Obstructive Sleep Apnea.Life (Basel, Switzerland) · 2024Article
- Relationship of serum 25-hydroxyvitamin D, obesity with new-onset obstructive sleep apnea.International journal of obesity (2005) · 2024Article
- Association between vitamin D and knee osteoarthritis in Indian population: A systematic review and meta-analysis.Journal of clinical orthopaedics and trauma · 2023Review
- Associations between serum vitamin D status and the cardiometabolic profile of patients with obstructive sleep apnea.Hormones (Athens, Greece) · 2023Article
- Influence of sunlight on the association between 25-hydroxyvitamin D levels and sleep quality in Brazilian adults: A population-based study.Nutrition (Burbank, Los Angeles County, Calif.) · 2023Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective was to determine whether OSA patients have a low serum vitamin D level by systematic review and meta-analysis.
methodsThis study searched the following electronic bibliographic databases: Embase, Medline, Web of Science, PubMed, VIP, Wanfang, CNKI and SinoMed. All data were searched between January 2000 and August 2020. The quality of the included studies was estimated by two researchers according to the Newcastle-Ottawa Scale and Agency for Healthcare Research and Quality. All qualified studies and statistical analyses were conducted using RevMan 5.2.
resultsTwenty-nine eligible studies compromising 6717 participants met the inclusion criteria of the meta-analysis. The results revealed that the serum 25(OH)D level was significantly lower in OSA patients than the controls. According to the severity of the disease, subgroup analysis was performed; the results demonstrated that the serum 25(OH)D level was not decreased in mild OSA patients compared with the controls, while the serum 25(OH)D level in moderate and severe OSA patients was lower than that in the controls. Furthermore, based on ethnicity, BMI, PSG type, study quality and latitude, the subjects were divided into different subgroups for meta-analysis. The results revealed that the serum 25(OH)D level in all OSA subgroups was decreased compared with that in the control group.
conclusionsThe present meta-analysis shows that the serum vitamin D level was different between OSA patients and healthy people. OSA patients could have a low serum vitamin D level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.