Evidence map›Paper›PMID 33167926›Full record

ArticleBMC pregnancy and childbirth2020

The impact of TSH levels on clinical outcomes 14 days after frozen-thawed embryo transfer.

Yuchao Zhang, Wenbin Wu, Yanli Liu, Yichun Guan, Xingling Wang, Liting Jia

Open access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yuchao ZhangDepartment of Reproductive Medicine, the Third Affiliated Hospital of Zhengzhou University, No.7 Kangfuqian Street, Erqi, Henan, Zhengzhou, China.
Wenbin WuDepartment of Reproductive Medicine, the Third Affiliated Hospital of Zhengzhou University, No.7 Kangfuqian Street, Erqi, Henan, Zhengzhou, China.
Yanli LiuDepartment of Reproductive Medicine, the Third Affiliated Hospital of Zhengzhou University, No.7 Kangfuqian Street, Erqi, Henan, Zhengzhou, China.
Yichun GuanDepartment of Reproductive Medicine, the Third Affiliated Hospital of Zhengzhou University, No.7 Kangfuqian Street, Erqi, Henan, Zhengzhou, China.
Xingling WangDepartment of Reproductive Medicine, the Third Affiliated Hospital of Zhengzhou University, No.7 Kangfuqian Street, Erqi, Henan, Zhengzhou, China. wangxl3661@163.com.
Liting JiaNeonatal screening center, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Third Affiliated Hospital of Zhengzhou University · CN

Funding

the Joint Project by the Third Affiliated Hospital of Zhengzhou University and Health Commission of Henan Province LHGJ20190400
6 · The paper itself

Abstract

backgroundThe aim of this study was to investigate the impact of TSH levels on clinical outcomes 14 days after frozen-thawed embryo transfer.

methodsBlood samples were collected on the first visit to our department and 14 days after embryo transfer. Women were divided into three groups based on D14 TSH levels, which were compared to basal TSH levels in groups with different clinical outcomes. TSH levels between pregnant and nonpregnant women were also compared.

resultsThe clinical pregnancy rate in women with lower TSH levels 14 days after transfer was slightly but significantly lower (56%, P = 0.05) compared to those with higher TSH levels. Furthermore, TSH levels were significantly elevated 14 days after transfer compared to basal TSH levels in pregnant women and in women who successfully became pregnant (P < 0.001, respectively).

conclusionsElevated TSH levels 14 days after embryo transfer compared to basal TSH levels seem to play a protective role and predict favorable clinical outcomes under specific conditions.

Indexed as

Pregnancy RateAbortion, SpontaneousAdultBiomarkersCryopreservationEmbryo TransferFemaleFertilization in VitroHumansPredictive Value of TestsPregnancyPrognosisProtective FactorsRetrospective StudiesRisk AssessmentThyrotropinBiomarkersThyrotropin14 daysclinical pregnancyfrozen-thawed embryo transfermiscarriageTSH

Identifiers

PMID33167926
PMCPMC7653845
OpenAlexW3102231544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.