Evidence map›Paper›PMID 33167600›Full record

ArticleAnimals : an open access journal from MDPI2020

Effect of DL-Methionine Supplementation on Tissue and Plasma Antioxidant Status and Concentrations of Oxidation Products of Cholesterol and Phytosterols in Heat-Processed Thigh Muscle of Broilers.

Johanna O Zeitz, Tamara Ehbrecht, Anne Fleischmann, Erika Most, Denise K Gessner, Silvia Friedrichs, Marion Sparenberg, Klaus Failing, Rose Whelan, Dieter Lütjohann and 1 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Johanna O ZeitzInstitute of Animal Nutrition and Nutritional Physiology, Justus Liebig University, D-35392 Giessen, Germany.
Tamara EhbrechtInstitute of Animal Nutrition and Nutritional Physiology, Justus Liebig University, D-35392 Giessen, Germany.
Anne FleischmannInstitute of Animal Nutrition and Nutritional Physiology, Justus Liebig University, D-35392 Giessen, Germany.
Erika MostInstitute of Animal Nutrition and Nutritional Physiology, Justus Liebig University, D-35392 Giessen, Germany.
Denise K GessnerInstitute of Animal Nutrition and Nutritional Physiology, Justus Liebig University, D-35392 Giessen, Germany.ORCID 0000-0002-7934-1304
Silvia FriedrichsInstitute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, D-53127 Bonn, Germany.
Marion SparenbergUnit of Biomathematics and Data Processing, Faculty of Veterinary Medicine, Justus Liebig University, D-35392 Giessen, Germany.
Klaus FailingUnit of Biomathematics and Data Processing, Faculty of Veterinary Medicine, Justus Liebig University, D-35392 Giessen, Germany.
Rose WhelanEvonik Operations GmbH, D-63457 Hanau-Wolfgang, Germany.ORCID 0000-0001-8812-403X
Dieter LütjohannInstitute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, D-53127 Bonn, Germany.ORCID 0000-0002-7941-8308
Klaus EderInstitute of Animal Nutrition and Nutritional Physiology, Justus Liebig University, D-35392 Giessen, Germany.ORCID 0000-0003-3246-4136
Justus-Liebig-Universität Gießen · DEUniversity Hospital Bonn · DEEvonik (Germany) · DE

Funding

Evonik Industries EVONIK Trial no. 03 53 16004
6 · The paper itself

Abstract

In this study, the hypothesis that supplementation with methionine (Met) as DL-Met (DLM) in excess of the National Research Council (NRC) recommendations improves the antioxidant system in broilers was investigated. Day-old male Cobb-500 broilers (n = 72) were divided into three groups which were fed a control diet or diets supplemented with two levels of DLM in which the concentrations of Met + Cys exceeded the recommendations of NRC by 15-20% (group DLM 1) or 30-40% (group DLM 2), respectively. The three groups of broilers did not show differences in body weight gains, feed intake, and feed conversion ratio. However, broilers of groups DLM 1 and DLM 2 had higher concentrations of glutathione (GSH) in liver and thigh muscle and lower concentrations of cholesterol oxidation products (COPs) in heat-processed thigh muscle than broilers of the control group. Concentrations of several oxidation products of phytosterols in heat-processed thigh muscle were also reduced in groups DLM 1 and DLM 2; however, the concentration of total oxidation products of phytosterols was not different between the three groups. The study shows that DLM supplementation improved the antioxidant status due to an increased formation of GSH and reduced the formation of COPs during heat-processing in thigh muscle.

Indexed as

antioxidantsbroilercholesterol oxidation productsmethioninephytosterol oxidation products

Identifiers

PMID33167600
PMCPMC7694460
OpenAlexW3095885291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.