ReviewViruses2020
Monkeypox Virus in Nigeria: Infection Biology, Epidemiology, and Evolution.
Review in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 384 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
384 citing papers in PubMed, 4 syntheses or guidelines pooled it, 795 citations in OpenAlex.
- Mpox vaccine acceptance and its predictors among people who have risky sexual practices: A systematic review and meta-analysis.Human vaccines & immunotherapeutics · 2025Pooled it
- Dynamics of Mpox infection in Nigeria: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Mpox vaccine acceptance among healthcare workers: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Monkeypox-Induced Myocarditis: A Systematic Review.Current problems in cardiology · 2023Pooled it
- A comprehensive overview of monkeypox virus disease.Tropical medicine and health · 2026Review
- How to utilise the limited supply of vaccines for Mpox control in Thailand among high-risk GBMSM.Infectious Disease Modelling · 2026Article
- A hybrid machine learning framework with two-step feature selection for identifying key biomarkers and drug targets in monkeypox.Biochemistry and biophysics reports · 2026Article
- MMF inhibits poxvirus infection by disrupting IMPDH2 interaction with USP5 and inducing its rod-and-ring assemblies.Virologica Sinica · 2026Article
- Development and preliminary clinical validation of A29L mAb-based ELISA and lateral flow immunoassays for monkeypox virus detection.Microbiology spectrum · 2026Article
- Emergence of Lineage E.4 and Structural Plasticity of A28L Protein in Mpox Virus: Characterization of LCR7 Length Polymorphisms Across Lineages - Shenzhen City, Guangdong Province, China, 2023-2025.China CDC weekly · 2026Article
- Mpox emergence, epidemiology, biology, clinical features and control.Nature reviews. Microbiology · 2026Review
- Antiviral innate immunity and adaptive immune responses against monkeypox and viral immune evasion.World journal of virology · 2026Review
- A Global Health Alert on the Re-Emergence of Mpox a Viral Zoonotic Illness Its Prevention and Management: A Narrative Review.Health science reports · 2026Article
- A deep learning approach for solving a fractional order Monkeypox transmission model using a harmonic neural network optimized with SGDM.Scientific reports · 2026Article
- Immunoinformatics driven multi-epitope vaccine design targeting clade IIb Mpox variant.Scientific reports · 2026Article
- Global complications among patients with mpox: a systematic review and meta-analysis.EClinicalMedicine · 2026Article
- Development of monoclonal antibody-based methods for detecting mpox virus.Biosafety and health · 2026Article
- Monkeypox (Mpox), a Resurging Global Public Health Concern: An Updated Outlook Through 2025.Current issues in molecular biology · 2026Review
- Cellular lipids: fundamental host factors for monkeypox virus replication and pathogenesis.Archives of microbiology · 2026Review
- Protective efficacy of a genetically modified attenuated vaccinia virus Tiantan strain against monkeypox virus challenge in a small animal model.Journal of virology · 2026Article
324 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member of orthopoxvirus genus. The reemergence of MPXV in 2017 (at Bayelsa state) after 39 years of no reported case in Nigeria, and the export of travelers' monkeypox (MPX) from Nigeria to other parts of the world, in 2018 and 2019, respectively, have raised concern that MPXV may have emerged to occupy the ecological and immunological niche vacated by smallpox virus. This review X-rays the current state of knowledge pertaining the infection biology, epidemiology, and evolution of MPXV in Nigeria and worldwide, especially with regard to the human, cellular, and viral factors that modulate the virus transmission dynamics, infection, and its maintenance in nature. This paper also elucidates the role of recombination, gene loss and gene gain in MPXV evolution, chronicles the role of signaling in MPXV infection, and reviews the current therapeutic options available for the treatment and prevention of MPX. Additionally, genome-wide phylogenetic analysis was undertaken, and we show that MPXV isolates from recent 2017 outbreak in Nigeria were monophyletic with the isolate exported to Israel from Nigeria but do not share the most recent common ancestor with isolates obtained from earlier outbreaks, in 1971 and 1978, respectively. Finally, the review highlighted gaps in knowledge particularly the non-identification of a definitive reservoir host animal for MPXV and proposed future research endeavors to address the unresolved questions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.