Evidence map›Paper›PMID 33167468›Full record

ArticleCells2020

Controlling the Switch from Neurogenesis to Pluripotency during Marmoset Monkey Somatic Cell Reprogramming with Self-Replicating mRNAs and Small Molecules.

Stoyan Petkov, Ralf Dressel, Ignacio Rodriguez-Polo, Rüdiger Behr

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Stoyan PetkovPlatform Degenerative Diseases, German Primate Center, GmbH, Leibniz Institute for Primate Research, 37077 Göttingen, Germany.ORCID 0000-0001-7551-7862
Ralf DresselGerman Center for Cardiovascular Research (DZHK), partner site Göttingen, 37077 Göttingen, Germany.ORCID 0000-0002-1651-1214
Ignacio Rodriguez-PoloPlatform Degenerative Diseases, German Primate Center, GmbH, Leibniz Institute for Primate Research, 37077 Göttingen, Germany.ORCID 0000-0003-1254-4972
Rüdiger BehrPlatform Degenerative Diseases, German Primate Center, GmbH, Leibniz Institute for Primate Research, 37077 Göttingen, Germany.ORCID 0000-0001-8816-6619
German Primate Center · DEUniversitätsmedizin Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Induced pluripotent stem cells (iPSCs) hold enormous potential for the development of cell-based therapies; however, the safety and efficacy of potential iPSC-based treatments need to be verified in relevant animal disease models before their application in the clinic. Here, we report the derivation of iPSCs from common marmoset monkeys (

Indexed as

Cellular ReprogrammingNeurogenesisAnimalsBiomarkersCallithrixCell DifferentiationCell LineageGene Expression RegulationInduced Pluripotent Stem CellsKaryotypingKruppel-Like Factor 4RNA, MessengerSmall Molecule LibrariesBiomarkersKLF4 protein, humanKruppel-Like Factor 4RNA, MessengerSmall Molecule LibrariesiPSCsmarmosetnonhuman primatereprogrammingVEE-mRNA

Identifiers

PMID33167468
PMCPMC7694496
OpenAlexW3095166812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.