Evidence map›Paper›PMID 33167391›Full record

ArticleNutrients2020

Understanding the Fate of Almond (

Domenico Trombetta, Antonella Smeriglio, Marcella Denaro, Roberto Zagami, Mara Tomassetti, Rosa Pilolli, Elisabetta De Angelis, Linda Monaci, Giuseppina Mandalari

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Review
  6. The Digestibility ofNutrients · 2021
    Article
  7. Antioxidant and Anti-Inflammatory Activity ofAntioxidants (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Domenico TrombettaDepartment of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Via Giovanni Palatucci, 98168 Messina, Italy.ORCID 0000-0003-4358-5224
Antonella SmeriglioDepartment of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Via Giovanni Palatucci, 98168 Messina, Italy.ORCID 0000-0002-9756-304X
Marcella DenaroDepartment of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Via Giovanni Palatucci, 98168 Messina, Italy.
Roberto ZagamiCNR-ISMN c/o Department of Chemical, Biological, Pharmaceutical and Environmental Sciences of the University of Messina, V.le F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Mara TomassettiDompé Farmaceutici S.p.A., Via Pietro Castellino, 80131 Napoli, Italy.
Rosa PilolliInstitute of Sciences of Food Production, National Research Council of Italy (ISPA-CNR), via Giovanni Amendola 122/O, 70126 Bari, Italy.ORCID 0000-0002-6789-1472
Elisabetta De AngelisInstitute of Sciences of Food Production, National Research Council of Italy (ISPA-CNR), via Giovanni Amendola 122/O, 70126 Bari, Italy.ORCID 0000-0003-1290-4544
Linda MonaciInstitute of Sciences of Food Production, National Research Council of Italy (ISPA-CNR), via Giovanni Amendola 122/O, 70126 Bari, Italy.ORCID 0000-0001-5650-7909
Giuseppina MandalariDepartment of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Via Giovanni Palatucci, 98168 Messina, Italy.ORCID 0000-0001-5663-3702
University of Messina · ITInstitute of Sciences of Food Production · ITDompé (Italy) · IT

Funding

Almond Board of California 2018
6 · The paper itself

Abstract

backgroundAlmond kernels contain phytochemicals with positive health effects in relation to heart disease, diabetes and obesity. Several studies have previously highlighted that almond cell wall encapsulation during digestion and particle size are factors associated with these benefits. In the present study, we have characterized almond oleosomes, natural oil droplets abundant in plants, and we have investigated their integrity during simulated gastrointestinal digestion.

methodsOleosomes were visualized on the almond seed surface by imaging mass spectrometry analysis, and then characterized in terms of droplet size distribution by dynamic light scattering and protein profile by liquid chromatography high-resolution tandem mass spectrometry analysis.

resultsThe almond oleosomes' distribution remained monomodal after in vitro mastication, whereas gastric and duodenal digestion led to a bimodal distribution, albeit characterized mainly by a prevalent population with a droplet size decrease related to a rearrangement of the protein profile. Oleosins, structural proteins found in plant oil bodies, persisted unchanged during simulated mastication, with the appearance of new prunin isoforms after gastric and duodenal digestion.

conclusionsThe rearrangement of the protein profile could limit lipid bioaccessibility. The data improve our understanding of the behavior of almond lipids during gastrointestinal digestion, and may have implications for energy intake and satiety imparted by almonds.

Indexed as

DigestionDuodenumElectrophoresis, Polyacrylamide GelHumansHydrodynamicsLipid DropletsMasticationParticle SizePlant ProteinsPrunus dulcisSeedsPlant Proteinsalmondsbioaccessibilityin vitro digestionoleosomes

Identifiers

PMID33167391
PMCPMC7694400
OpenAlexW3097858816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.