Evidence map›Paper›PMID 33166716›Full record

ArticleAnnals of epidemiology2021

Incorporating patient reporting patterns to evaluate spatially targeted TB interventions.

Isabella Gomes, Mehdi Reja, Sourya Shrestha, Jeffrey Pennington, Youngji Jo, Yeonsoo Baik, Shamiul Islam, Ahmadul Hasan Khan, Abu Jamil Faisel, Oscar Cordon and 4 more

Abstract read
In one paragraph

Article in Annals of epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Isabella GomesDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Mehdi RejaChallenge TB Project, Bangladesh; Interactive Research & Development (IRD), Bangladesh.
Sourya ShresthaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. Electronic address: sshres14@jh.edu.
Jeffrey PenningtonDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Youngji JoDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Yeonsoo BaikDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Shamiul IslamNational Tuberculosis Control Program (NTP), Bangladesh.
Ahmadul Hasan KhanNational Tuberculosis Control Program (NTP), Bangladesh.
Abu Jamil FaiselChallenge TB Project, Bangladesh; Interactive Research & Development (IRD), Bangladesh.
Oscar CordonChallenge TB Project, Bangladesh; FHI360, Santo Domingo, Dominican Republic.
Tapash RoyInteractive Research & Development (IRD), Bangladesh.
Pedro SuarezManagement Sciences for Health (MSH), Arlington, VA.
Hamidah HussainIRD Global, Singapore.
David DowdyDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.

Funding

BU Clinical HIV/AIDS Research Training Program (BU-CHART)T32AI052074 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Benjamin P. Linas · 2003 to 2026
$6.7M
Optimal Medication Dispensing for People Living with HIV with and without Other Chronic Diseases in Zambia: A Mathematical ModelF32MH128120 · NIMH · BOSTON MEDICAL CENTER · PI JO, YOUNGJI · 2021 to 2022
$150k
NIAID NIH HHS T32 AI052074NIMH NIH HHS F32 MH128120
6 · The paper itself

Abstract

purposeTuberculosis (TB) is geographically heterogeneous, and geographic targeting can improve the impact of TB interventions. However, standard TB notification data may not sufficiently capture this heterogeneity. Better understanding of patient reporting patterns (discrepancies between residence and place of presentation) may improve our ability to use notifications to appropriately target interventions.

methodsUsing demographic data and TB reports from Dhaka North City Corporation and Dhaka South City Corporation, we identified wards of high TB incidence and developed a TB transmission model. We calibrated the model to patient-level data from selected wards under four different reporting pattern assumptions and estimated the relative impact of targeted versus untargeted active case finding.

resultsThe impact of geographically targeted interventions varied substantially depending on reporting pattern assumptions. The relative reduction in TB incidence, comparing targeted with untargeted active case finding in Dhaka North City Corporation, was 1.20, assuming weak correlation between reporting and residence, versus 2.45, assuming perfect correlation. Similar patterns were observed in Dhaka South City Corporation (1.03 vs. 2.08).

conclusionsMovement of individuals seeking TB diagnoses may substantially affect ward-level TB transmission. Better understanding of patient reporting patterns can improve estimates of the impact of targeted interventions in reducing TB incidence. Incorporating high-quality patient-level data is critical to optimizing TB interventions.

Indexed as

TuberculosisBangladeshHumansIncidenceProgram EvaluationSpatial AnalysisTuberculosis heterogeneityTuberculosis in DhakaTuberculosis patient-level reporting

Identifiers

PMID33166716
PMCPMC9612399

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.