ArticleNeurobiology of disease2021
Increased neuronal activity in motor cortex reveals prominent calcium dyshomeostasis in tauopathy mice.
Open access · goldAbstract read
In one paragraph
Article in Neurobiology of disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 16 citations in OpenAlex.
- Tau pSer396 and pSer404 Define Distinct Epitope Regions Linked to Different Antibody Functions.bioRxiv : the preprint server for biology · 2026Article
- Cell-Type-Selective Cortical Pathology and Functional Deficits in Synucleinopathy.bioRxiv : the preprint server for biology · 2026Article
- Clearing truncated tau protein restores neuronal function and prevents microglia activation in tauopathy mice.Cell reports · 2025Article
- Twenty years of therapeutic development in tauopathy mouse models: a scoping review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Exposure to COVID-19 virus-like particles modulates firing patterns of cortical neurons in the mouse brain.Communications biology · 2025Article
- Dysregulated calcium signaling in the aged primate association cortices: vulnerability to Alzheimer's disease neuropathology.Frontiers in aging neuroscience · 2025Review
- Article
- Neuronal hypofunction and network dysfunction in a mouse model at an early stage of tauopathy.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Tau-targeting therapies for Alzheimer disease: current status and future directions.Nature reviews. Neurology · 2023Review
- Tauopathy severely disrupts homeostatic set-points in emergent neural dynamics but not in the activity of individual neurons.bioRxiv : the preprint server for biology · 2023Article
- Targeting tau only extracellularly is likely to be less efficacious than targeting it both intra- and extracellularly.Seminars in cell & developmental biology · 2022Review
- Neuronal α-amylase is important for neuronal activity and glycogenolysis and reduces in presence of amyloid beta pathology.Aging cell · 2021Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Qian WuNew York University Grossman School of Medicine, Department of Neuroscience and Physiology, Science Building, 435 East 30th Street, New York, NY 10016, United States of America; New York University Grossman School of Medicine, Neuroscience Institute, Science Building, 435 East 30th Street, New York, NY 10016, United States of America. Electronic address: qian.wu@nyumc.org.
Yang BaiNew York University Grossman School of Medicine, Department of Neuroscience and Physiology, Science Building, 435 East 30th Street, New York, NY 10016, United States of America; New York University Grossman School of Medicine, Neuroscience Institute, Science Building, 435 East 30th Street, New York, NY 10016, United States of America; New York University Grossman School of Medicine, Skirball Institute, 550 First Avenue, New York, NY 10016, United States of America. Electronic address: yang.bai@nyumc.org.
Wei LiNew York University Grossman School of Medicine, Department of Neuroscience and Physiology, Science Building, 435 East 30th Street, New York, NY 10016, United States of America; New York University Grossman School of Medicine, Neuroscience Institute, Science Building, 435 East 30th Street, New York, NY 10016, United States of America; New York University Grossman School of Medicine, Skirball Institute, 550 First Avenue, New York, NY 10016, United States of America.
Erin E CongdonNew York University Grossman School of Medicine, Department of Neuroscience and Physiology, Science Building, 435 East 30th Street, New York, NY 10016, United States of America; New York University Grossman School of Medicine, Neuroscience Institute, Science Building, 435 East 30th Street, New York, NY 10016, United States of America. Electronic address: erin.congdon@nyumc.org.
Wenke LiuNew York University Grossman School of Medicine, Department of Psychiatry, 550 First Avenue, New York, NY 10016, United States of America. Electronic address: Wenke.Liu@nyumc.org.
Yan LinNew York University Grossman School of Medicine, Department of Neuroscience and Physiology, Science Building, 435 East 30th Street, New York, NY 10016, United States of America; New York University Grossman School of Medicine, Neuroscience Institute, Science Building, 435 East 30th Street, New York, NY 10016, United States of America. Electronic address: Yan.Lin@nyumc.org.
Changyi JiNew York University Grossman School of Medicine, Department of Neuroscience and Physiology, Science Building, 435 East 30th Street, New York, NY 10016, United States of America; New York University Grossman School of Medicine, Neuroscience Institute, Science Building, 435 East 30th Street, New York, NY 10016, United States of America. Electronic address: changyi.ji@nyumc.org.
Wen-Biao GanNew York University Grossman School of Medicine, Department of Neuroscience and Physiology, Science Building, 435 East 30th Street, New York, NY 10016, United States of America; New York University Grossman School of Medicine, Neuroscience Institute, Science Building, 435 East 30th Street, New York, NY 10016, United States of America; New York University Grossman School of Medicine, Skirball Institute, 550 First Avenue, New York, NY 10016, United States of America. Electronic address: wenbiao.gan@nyumc.org.
Einar M SigurdssonNew York University Grossman School of Medicine, Department of Neuroscience and Physiology, Science Building, 435 East 30th Street, New York, NY 10016, United States of America; New York University Grossman School of Medicine, Neuroscience Institute, Science Building, 435 East 30th Street, New York, NY 10016, United States of America; Department of Psychiatry, New York University Grossman School of Medicine, New York, NY 10016, United States of America. Electronic address: einar.sigurdsson@nyumc.org.
New York University · US
Funding
Research Supplement to Promote Diversity in Health-Related ResearchR01AG032611 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Einar M Sigurdsson · 2008 to 2026
$9.7MEpitope-Specific Targeting of Tau Aggregates.R01NS077239 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Einar M Sigurdsson · 2011 to 2026
$7.9MNIA NIH HHS R01 AG032611NINDS NIH HHS R01 NS077239
Abstract
Perturbed neuronal Ca
Indexed as
AnimalsBrainCalciumHomeostasisHumansMiceMice, TransgenicMotor ActivityMotor CortexNeuronsTauopathiestau ProteinsCalciumtau ProteinsAlzheimer's diseaseAntibodyCa(2+)Frontotemporal dementiaMiceTauTwo-photon imaging
Identifiers
What OpenQuestion holds
Textmetadata
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.