ArticlePLoS biology2020
Monitor for COVID-19 vaccine resistance evolution during clinical trials.
Article in PLoS biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Impact of lockdown on key workers: findings from the COVID-19 survey in four UK national longitudinal studies.Journal of epidemiology and community health · 2021Pooled it
- A Deferred-Vaccination Design to Assess Durability of COVID-19 Vaccine Effect After the Placebo Group Is Vaccinated.Annals of internal medicine · 2021Pooled it
- Evolution of Antiviral Drug Resistance in SARS-CoV-2.Viruses · 2025Review
- Exceptions to the rule: When does resistance evolution not undermine antibiotic therapy in human bacterial infections?Evolution letters · 2024Article
- Building pyramids against the evolutionary emergence of pathogens.Proceedings. Biological sciences · 2024Article
- Vaccines Alone Cannot Slow the Evolution of SARS-CoV-2.Vaccines · 2023Article
- The future of evolutionary medicine: sparking innovation in biomedicine and public health.Frontiers in science · 2023Article
- COVID-19 exit strategy during vaccine implementation: a balance between social distancing and herd immunity.Archives of virology · 2022Review
- Pathogen evolution during vaccination campaigns.PLoS biology · 2022Article
- Achieving Global Vaccine Equity: The Case for an International Pandemic Treaty.The Yale journal of biology and medicine · 2022Review
- When do children avoid infection risks: Lessons for schools during the COVID-19 pandemic.iScience · 2022Review
- COVID-19 vaccinations: The unknowns, challenges, and hopes.Journal of medical virology · 2022Review
- An Overview of Antiviral Peptides and Rational Biodesign Considerations.Biodesign research · 2022Review
- Assessing the risk of vaccine-driven virulence evolution in SARS-CoV-2.Royal Society open science · 2022Article
- Article
- Post-COVID-19 vaccination occurrence of splenic infarction due to arterial thrombosis.BMJ case reports · 2021Article
- Modelling COVID-19 dynamics and potential for herd immunity by vaccination in Austria, Luxembourg and Sweden.Journal of theoretical biology · 2021Article
- SARS-CoV-2 virulence evolution: Avirulence theory, immunity and trade-offs.Journal of evolutionary biology · 2021Review
- An Update on Pharmacological Relevance and Chemical Synthesis of Natural Products and Derivatives with Anti SARS-CoV-2 Activity.ChemistrySelect · 2021Review
- Understanding the devastating second wave of COVID-19 pandemic in India.American journal of human biology : the official journal of the Human Biology Council · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Although less common than the evolution of antimicrobial drug resistance, vaccine resistance can and has evolved. How likely is it that COVID-19 vaccines currently in development will be undermined by viral evolution? We argue that this can be determined by repurposing samples that are already being collected as part of clinical trials. Such information would be useful for prioritizing investment among candidate vaccines and maximizing the potential long-term impact of COVID-19 vaccines.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.