Evidence map›Paper›PMID 33166197›Full record

ArticleJCO clinical cancer informatics2020

Joint Imaging Platform for Federated Clinical Data Analytics.

Jonas Scherer, Marco Nolden, Jens Kleesiek, Jasmin Metzger, Klaus Kades, Verena Schneider, Michael Bach, Oliver Sedlaczek, Andreas M Bucher, Thomas J Vogl and 51 more

Abstract readMulticenter Study
In one paragraph

Article in JCO clinical cancer informatics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Radiological data processing system: lifecycle management and annotation.International journal of computer assisted radiology and surgery · 2025
    Article
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  4. Article
  5. Multi-modal dataset creation for federated learning with DICOM-structured reports.International journal of computer assisted radiology and surgery · 2025
    Article
  6. Article
  7. Article
  8. Article
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  10. Review
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  13. CODA: an open-source platform for federated analysis and machine learning on distributed healthcare data.Journal of the American Medical Informatics Association : JAMIA · 2024
    Article
  14. Review
  15. Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

61 authors.

Jonas SchererDivision of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany.ORCID 0000-0001-8608-6252
Marco NoldenDivision of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany.ORCID 0000-0001-9629-0564
Jens KleesiekGerman Cancer Consortium, Heidelberg, Germany.
Jasmin MetzgerDivision of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany.
Klaus KadesDivision of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany.
Verena SchneiderGerman Cancer Consortium, Heidelberg, Germany.
Michael BachGerman Cancer Consortium, Heidelberg, Germany.
Oliver SedlaczekGerman Cancer Consortium, Heidelberg, Germany.
Andreas M BucherGerman Cancer Consortium, Heidelberg, Germany.ORCID 0000-0001-9194-5955
Thomas J VoglGerman Cancer Consortium, Heidelberg, Germany.
Frank GrünwaldGerman Cancer Consortium, Heidelberg, Germany.
Jens-Peter KühnGerman Cancer Consortium, Heidelberg, Germany.ORCID 0000-0003-3258-930X
Ralf-Thorsten HoffmannGerman Cancer Consortium, Heidelberg, Germany.ORCID 0000-0003-3150-4263
Jörg KotzerkeGerman Cancer Consortium, Heidelberg, Germany.
Oliver BethgeGerman Cancer Consortium, Heidelberg, Germany.
Lars SchimmöllerGerman Cancer Consortium, Heidelberg, Germany.ORCID 0000-0001-7476-292X
Gerald AntochGerman Cancer Consortium, Heidelberg, Germany.
Hans-Wilhelm MüllerGerman Cancer Consortium, Heidelberg, Germany.
Andreas DaulGerman Cancer Consortium, Heidelberg, Germany.
Konstantin NikolaouGerman Cancer Consortium, Heidelberg, Germany.
Christian la FougèreGerman Cancer Consortium, Heidelberg, Germany.ORCID 0000-0001-7519-0417
Wolfgang G KunzGerman Cancer Consortium, Heidelberg, Germany.
Michael IngrischGerman Cancer Consortium, Heidelberg, Germany.ORCID 0000-0003-0268-9078
Balthasar SchachtnerGerman Cancer Consortium, Heidelberg, Germany.ORCID 0000-0002-8712-3948
Jens RickeGerman Cancer Consortium, Heidelberg, Germany.
Peter BartensteinGerman Cancer Consortium, Heidelberg, Germany.
Felix NensaGerman Cancer Consortium, Heidelberg, Germany.
Alexander RadbruchGerman Cancer Consortium, Heidelberg, Germany.
Lale UmutluGerman Cancer Consortium, Heidelberg, Germany.
Michael ForstingGerman Cancer Consortium, Heidelberg, Germany.
Robert SeifertGerman Cancer Consortium, Heidelberg, Germany.ORCID 0000-0001-5985-7701
Ken HerrmannGerman Cancer Consortium, Heidelberg, Germany.ORCID 0000-0002-9662-7259
Philipp MayerGerman Cancer Consortium, Heidelberg, Germany.ORCID 0000-0003-1957-1594
Hans-Ulrich KauczorGerman Cancer Consortium, Heidelberg, Germany.
Tobias PenzkoferGerman Cancer Consortium, Heidelberg, Germany.ORCID 0000-0001-9591-8575
Bernd HammGerman Cancer Consortium, Heidelberg, Germany.
Winfried BrennerGerman Cancer Consortium, Heidelberg, Germany.
Roman KloecknerGerman Cancer Consortium, Heidelberg, Germany.ORCID 0000-0001-5492-4792
Christoph DüberGerman Cancer Consortium, Heidelberg, Germany.
Mathias SchreckenbergerGerman Cancer Consortium, Heidelberg, Germany.
Rickmer BrarenGerman Cancer Consortium, Heidelberg, Germany.
Georgios KaissisGerman Cancer Consortium, Heidelberg, Germany.ORCID 0000-0001-8382-8062
Marcus MakowskiGerman Cancer Consortium, Heidelberg, Germany.
Matthias EiberGerman Cancer Consortium, Heidelberg, Germany.
Andrei GafitaGerman Cancer Consortium, Heidelberg, Germany.
Rupert TragerGerman Cancer Consortium, Heidelberg, Germany.
Wolfgang A WeberGerman Cancer Consortium, Heidelberg, Germany.
Jakob NeubauerGerman Cancer Consortium, Heidelberg, Germany.
Marco ReisertGerman Cancer Consortium, Heidelberg, Germany.
Michael BockGerman Cancer Consortium, Heidelberg, Germany.ORCID 0000-0001-9720-3506
Fabian BambergGerman Cancer Consortium, Heidelberg, Germany.
Jürgen HennigGerman Cancer Consortium, Heidelberg, Germany.ORCID 0000-0002-2273-3497
Philipp Tobias MeyerGerman Cancer Consortium, Heidelberg, Germany.
Juri RufGerman Cancer Consortium, Heidelberg, Germany.
Uwe HaberkornGerman Cancer Consortium, Heidelberg, Germany.
Stefan O SchoenbergGerman Cancer Consortium, Heidelberg, Germany.
Tristan KuderGerman Cancer Consortium, Heidelberg, Germany.ORCID 0000-0001-6439-8124
Peter NeherDivision of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany.ORCID 0000-0002-5285-7554
Ralf FlocaDivision of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany.ORCID 0000-0003-3218-3377
Heinz-Peter SchlemmerMedical Faculty Heidelberg, University of Heidelberg, Heidelberg, Germany.
Klaus Maier-HeinDivision of Medical Image Computing, German Cancer Research Center, Heidelberg, Germany.ORCID 0000-0002-6626-2463

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeImage analysis is one of the most promising applications of artificial intelligence (AI) in health care, potentially improving prediction, diagnosis, and treatment of diseases. Although scientific advances in this area critically depend on the accessibility of large-volume and high-quality data, sharing data between institutions faces various ethical and legal constraints as well as organizational and technical obstacles.

methodsThe Joint Imaging Platform (JIP) of the German Cancer Consortium (DKTK) addresses these issues by providing federated data analysis technology in a secure and compliant way. Using the JIP, medical image data remain in the originator institutions, but analysis and AI algorithms are shared and jointly used. Common standards and interfaces to local systems ensure permanent data sovereignty of participating institutions.

resultsThe JIP is established in the radiology and nuclear medicine departments of 10 university hospitals in Germany (DKTK partner sites). In multiple complementary use cases, we show that the platform fulfills all relevant requirements to serve as a foundation for multicenter medical imaging trials and research on large cohorts, including the harmonization and integration of data, interactive analysis, automatic analysis, federated machine learning, and extensibility and maintenance processes, which are elementary for the sustainability of such a platform.

conclusionThe results demonstrate the feasibility of using the JIP as a federated data analytics platform in heterogeneous clinical information technology and software landscapes, solving an important bottleneck for the application of AI to large-scale clinical imaging data.

Indexed as

Artificial IntelligenceRadiologyData ScienceDelivery of Health CareGermanyHumans

Identifiers

PMID33166197
PMCPMC7713526

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.