ArticleJournal of experimental botany2021
The transcription factor WRKY75 positively regulates jasmonate-mediated plant defense to necrotrophic fungal pathogens.
Article in Journal of experimental botany, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.
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76 citing papers in PubMed, 133 citations in OpenAlex.
- GIGANTEA mediates WRKY-dependent transcriptional activation of leaf senescence.Plant signaling & behavior · 2026Article
- Tripartite Interaction Between Penicillium pinophilum-Host Plants and CMV-Y: A Model for Endophyte-Mediated Viral Biocontrol.Plant, cell & environment · 2026Article
- Article
- CsWRKY33 Integrates Immune Signalling and Metabolic Reprogramming to Enhance Tea Plant Resistance Against Colletotrichum camelliae.Plant, cell & environment · 2026Article
- Suppression of ZmJAZ12 Expression Modulates Jasmonic Acid and Salicylic Acid Signalling and Enhances Maize Resistance to Southern Corn Rust.Molecular plant pathology · 2026Article
- PsWRKY71 acts as a GA signaling component to promote bud break in tree peony (Paeonia suffruticosa).The New phytologist · 2026Article
- Direct avirulence effector-receptor interaction confers wheat immunity against insects.Science advances · 2026Article
- A VvWRKY8-salicylic acid pathway amplification loop confers resistance to Plasmopara viticola in grapevine.Molecular horticulture · 2026Article
- PsWRKY75 orchestrates lignin biosynthesis and H₂O₂ metabolism to modulate disease resistance: a physiological and biochemical mechanism in Prunus sibirica L.BMC plant biology · 2026Article
- Integration of Spatiotemporal Multi-Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome-Mediated Stress Adaptation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- MdWRKY61 enhances apple resistance to Colletotrichum fructicola through jasmonic acid signaling pathway.Plant cell reports · 2026Article
- A multiplant transcriptomic atlas reveals conserved and lineage-specific defense architectures in response toProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Specialized Metabolic Reprogramming in Plant Immunity: Biosynthetic Networks, Spatiotemporal Regulation, and Quantitative Defense.Plants (Basel, Switzerland) · 2026Review
- Silica nanoparticles enhance resistance of Vitis vinifera to downy mildew.BMC plant biology · 2026Article
- The Jasmonate-Responsive SmMPK3-SmWRKY33 Module Positively Regulates Tanshinone Biosynthesis in Salvia miltiorrhiza.Plant biotechnology journal · 2026Article
- Host microenvironment in potato-Phytophthora infestans interaction revealed by single-cell spatiotemporal transcriptome.Nature plants · 2026Article
- Genome-Wide Analysis of theInternational journal of molecular sciences · 2025Article
- The transcription factor BnaWRKY75 enhances resistance to the necrotrophic pathogen Sclerotinia sclerotiorum by promoting salicylic acid biosynthesis in oilseed rape.Journal of experimental botany · 2025Article
- Manipulation of the Expression of Tryptophan Decarboxylase Boosts Grain Functional Quality and Stress Resilience Capacity of Wheat.Plant biotechnology journal · 2025Article
- Antimicrobial Peptides as Part of the Arsenal of Constitutive and Inducible Seed Defences in Tomato Seed Exudates Against Pathogens.Molecular plant pathology · 2025Article
16 more citing papers are in PubMed but not listed here.
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6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Necrotrophic fungi cause devastating diseases in both horticultural and agronomic crops, but our understanding of plant defense responses against these pathogens is still limited. In this study, we demonstrated that WRKY75 positively regulates jasmonate (JA)-mediated plant defense against necrotrophic fungal pathogens Botrytis cinerea and Alternaria brassicicola, and also affects the sensitivity of plants to JA-inhibited seed germination and root growth. Quantitative analysis indicated that several JA-associated genes, such as OCTADECANOID-RESPONSIVE ARABIDOPSIS (ORA59) and PLANT DEFENSIN 1.2A (PDF1.2), were significantly reduced in expression in wrky75 mutants, and enhanced in WRKY75 overexpressing transgenic plants. Immunoprecipitation assays revealed that WRKY75 directly binds to the promoter of ORA59 and represses itstranscription. In vivo and in vitro experiments suggested that WRKY75 interacts with several JASMONATE ZIM-domain proteins, repressors of the JA signaling pathway. We determined that JASMONATE-ZIM-DOMAIN PROTEIN 8 (JAZ8) represses the transcriptional function of WRKY75, thereby attenuating the expression of its regulation. Overexpression of JAZ8 repressed plant defense responses to B. cinerea. Our study provides evidence that WRKY75 functions as a critical component of the JA-mediated signaling pathway to positively regulate Arabidopsis defense responses to necrotrophic pathogens.
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