Evidence map›Paper›PMID 33165348›Full record

ArticleInternational journal of clinical and experimental pathology2020

Medullary thyroid carcinoma combined with papillary thyroid carcinoma: case report and literature review.

Jin Yao, Cheng-Fang Li, Jin-Jing Wang, Su-Yuan Zhang, Yong-Lin Li, Jing Yang, Hong Zheng

Open access · greenAbstract readCase Reports
In one paragraph

Article in International journal of clinical and experimental pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jin YaoDepartment of Pathology, Affiliated Hospital of Zunyi Medical University Guizhou Province, China.
Cheng-Fang LiDepartment of Pathology, Affiliated Hospital of Zunyi Medical University Guizhou Province, China.
Jin-Jing WangDepartment of Pathology, Affiliated Hospital of Zunyi Medical University Guizhou Province, China.
Su-Yuan ZhangDepartment of Pathology, Affiliated Hospital of Zunyi Medical University Guizhou Province, China.
Yong-Lin LiDepartment of Pathology, Fenggang County People's Hospital Zunyi City, Guizhou Province, China.
Jing YangDepartment of Pathology, Affiliated Hospital of Zunyi Medical University Guizhou Province, China.
Hong ZhengDepartment of Pathology, Affiliated Hospital of Zunyi Medical University Guizhou Province, China.
Zunyi Medical University · CNFirst People’s Hospital of Zunyi · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the clinicopathologic features, immunophenotype, (differential) diagnosis, pathogenesis, treatment, and follow-up of medullary thyroid carcinoma (MTC) combined with papillary thyroid carcinoma (PTC). A retrospective analysis of the clinical and pathologic features and immunophenotype was conducted in a patient with MTC and PTC. Relevant literature was also reviewed. Results of thyroid fine needle aspiration indicated malignant tumor in the right lobe of the thyroid, suggesting PTC; further analysis by biopsy confirmed this diagnosis. The left lobe exhibited MTC. Tumor metastases were absent from the lymph nodes of the left central area (0/2), and no tumor was present in the thymic tissue. In the right lobe and isthmus, PTC was observed, with a maximum infiltration diameter of 0.8 cm, and tumor metastases were absent from lymph nodes of the right central area (0/3). Immunohistochemistry of the left lobe was positive for calcitonin, CK, TTF-1, CD56, CgA, and Congo red, but negative for CK19, thyroglobulin, galectin-3, MC, and CEA, with a Ki-67 proliferation index of 1%. The right lobe was positive for CK19, galectin-3, and MC, but negative for CD56. The V600E mutation was detected in

Indexed as

differential diagnosisimmunophenotypeMedullary thyroid carcinomapapillary thyroid carcinomapathogenesis

Identifiers

PMID33165348
PMCPMC7642704
OpenAlexW3106455934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.