Evidence map›Paper›PMID 33164931›Full record

ArticleJournal of Alzheimer's disease : JAD2020

Impact of Patient Mild Cognitive Impairment on Physician Decision-Making for Treatment.

Emilie M Blair, Darin B Zahuranec, Kenneth M Langa, Jane Forman, Bailey K Reale, Colleen Kollman, Bruno Giordani, Deborah A Levine

Open access · greenAbstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Nurse Practitioners' Experiences Navigating Treatment Decision-Making Affecting Older People with Neurocognitive Disorders and Cancer.The Canadian journal of nursing research = Revue canadienne de recherche en sciences infirmieres · 2026
    Article
  3. Review
  4. Patient and Care Partner Perspective on Potential Undertreatment of Patients With Mild Cognitive Impairment for Cardiovascular Disease.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2024
    Article
  5. Article
  6. Article
  7. Influence of mild cognitive impairment on patient and care partner decision-making for acute ischemic stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Physician Diagnosis and Knowledge of Mild Cognitive Impairment.Journal of Alzheimer's disease : JAD · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Emilie M BlairUniversity of Michigan (U-M), Ann Arbor, MI, USA.
Darin B ZahuranecDepartment of Neurology and Stroke Program, U-M, Ann Arbor, MI, USA.
Kenneth M LangaDepartment of Internal Medicine and Cognitive Health Services Research Program, U-M Medical School, Ann Arbor, MI, USA.
Jane FormanDepartment of Internal Medicine and Cognitive Health Services Research Program, U-M Medical School, Ann Arbor, MI, USA.
Bailey K RealeDepartment of Internal Medicine and Cognitive Health Services Research Program, U-M Medical School, Ann Arbor, MI, USA.
Colleen KollmanKollman Research Services, Ann Arbor, MI, USA.
Bruno GiordaniDepartment of Psychiatry and Michigan Alzheimer's Disease Center, U-M, Ann Arbor, MI, USA.
Deborah A LevineDepartment of Neurology and Stroke Program, U-M, Ann Arbor, MI, USA.
Cal Humanities · USVA Ann Arbor Healthcare System · USClinical Research Services · DEInstitute for Healthcare Improvement · USUniversity of Michigan–Ann Arbor · US

Funding

The Effect of Lower Blood Pressure over the Life Course on Late-life Cognition in Blacks, Hispanics, and Whites (BP-COG)R01NS102715 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEVINE, DEBORAH ALLISON · 2017 to 2021
$3.8M
Decision Making for Cardiovascular Therapy in Adults with Mild Cognitive ImpairmentR01AG051827 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEVINE, DEBORAH ALLISON · 2016 to 2020
$3.6M
Prognosis and End-of-Life Decision Making in Intracerebral HemorrhageK23AG038731 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZAHURANEC, DARIN B · 2011 to 2015
$796k
The Predictors and Long-Term Trajectory of Poststroke Cognitive DeclineK23AG040278 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEVINE, DEBORAH ALLISON · 2012 to 2015
$637k
NIA NIH HHS K23 AG038731NIA NIH HHS K23 AG040278NIA NIH HHS R01 AG051827NINDS NIH HHS R01 NS102715
6 · The paper itself

Abstract

backgroundOlder patients with mild cognitive impairment (MCI) should receive evidence-based treatments when clinically indicated. However, patients with MCI appear less likely than cognitively normal patients to receive evidence-based treatments.

objectiveTo explore the influence of a patient's MCI diagnosis on physician decision-making.

methodsQualitative study of 18 physicians from cardiology, neurology, and internal medicine using semi-structured interviews. We sought to understand whether and how a patient's having MCI has influenced physicians' decisions about five categories of treatments or tests (surgery, invasive tests, non-invasive tests, rehabilitation, and preventive medication). We used qualitative content analysis to identify the unifying and recurrent themes.

resultsMost physician participants described MCI as influencing their recommendations for at least one treatment or test. We identified two major themes as factors that influenced physician recommendations in patients with MCI: Physicians assume that MCI patients' decreased cognitive ability will impact treatment; and physicians assume that MCI patients have poor health status and physical functioning that will impact treatment. These two themes were representative of physician beliefs that MCI patients have impaired independent decision-making, inability to adhere to treatment, inability to communicate treatment preferences, and increased risk and burden from treatment.

conclusionA patient's MCI diagnosis influences physician decision-making for treatment. Some physician assumptions about patients with MCI were not evidence-based. This phenomenon potentially explains why many patients with MCI get fewer effective treatments or tests than cognitively normal patients. Interventions that improve how physicians understand MCI and make decisions for treatments in patients with MCI are needed.

Indexed as

Clinical Decision-MakingCognitive DysfunctionHealthcare DisparitiesPhysiciansCardiologyEvidence-Based MedicineFemaleHumansInternal MedicineMaleNeurologyPilot ProjectsQualitative ResearchAgingdecision makingmild cognitive impairmenttreatment

Identifiers

PMID33164931
PMCPMC7952022
OpenAlexW3096670226

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.